Author

S. Rasool

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 4 Animal Behavior & Cognition· 1 Bioengineering· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 6 Organism:human· 3 Assay:proteomics· 3 Research Focus:cell signaling & trafficking· 2 Research Focus:drug response / drug discovery· 2 Approach:biophysical modeling· 1 Research Focus:chromatin & epigenetic regulation· 1 Assay:imaging· 1

Frequent Co-Authors

J.-F. Trempe· 4 shared E. A. Fon· 2 shared N. Croteau· 2 shared S. Veyron· 2 shared A. E. Carpenter· 1 shared A. Hajjar· 1 shared A. Khan· 1 shared A. Lee· 1 shared

Activity by Year

2021-2023 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 13 mutual co-author links

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4 shared papersBiochemistry

J.-F. Trempe

Mutual co-authors in cluster

Author profile →

6 papers

Recent·Most cited

Identification and structural characterization of small-molecule inhibitors of PINK1

S. Rasool, T. Shomali, L. Truong, N. Croteau, S. Veyron, J.-F. Trempe

This study identifies and characterizes small-molecule inhibitors of PINK1, revealing their mechanism of action and potential for developing PD therapeutics.

bioRxiv · Oct 2, 2023Biochemistry

nELISA: A high-throughput, high-plex platform enables quantitative profiling of the inflammatory secretome

M. Dagher, G. Ongo, N. Robichaud, J. Kong, W. Rho, I. Teahulos, A. Tavakoli, S. Bovaird, S. Merjaneh, A. Tan, K. Edwardson, C. Scheepers, A. Ng, A. Hajjar, B. Sow, , D. Juncker

nELISA enables high-throughput, high-plex protein profiling of the inflammatory secretome, revealing 447 significant cytokine responses across multiple donors and conditions.

bioRxiv · Apr 17, 2023 · PreprintBioengineering

Lights, Camera, Mirrors, Action! Toolbox for 3D Reconstruction and Analysis Using a Single Camera and Planar Mirrors

M. w. hussain, M. Naveed, A. Khan, T. H. Khan, M. L. Anjum, S. Rasool, A. Maqsood

The paper introduces a software toolbox for 3D reconstruction using a single camera and planar mirrors, enabling accurate analysis of high-speed animal movements.

bioRxiv · Mar 14, 2023 · PreprintAnimal Behavior & Cognition

Dissecting the interactions of PINK1 with the TOM complex in depolarized mitochondria

K. Maruszczak, M. Jung, S. Rasool, J.-F. Trempe, D. Rapaport

This study investigates how PINK1 interacts with the TOM complex in depolarized mitochondria, revealing the role of TOM70 and TOM40 in its association with the mitochondrial outer membrane.

bioRxiv · Jan 13, 2022 · PreprintBiochemistry

Selective localization of Mfn2 near PINK1 enable its preferential ubiquitination by Parkin on mitochondria

M. Vranas, Y. Lu, S. Rasool, N. Croteau, J. D. Krett, V. Sauve, K. Gehring, E. A. Fon, T. M. Durcan, J.-F. Trempe

The paper identifies Mfn2 as a preferred Parkin substrate due to its proximity to PINK1, which facilitates Parkin activation and ubiquitination on mitochondria.

bioRxiv · Aug 25, 2021Biochemistry

Structure of PINK1 reveals autophosphorylation dimer and provides insights into binding to the TOM complex

S. Rasool, S. Veyron, N. Soya, M. Eldeeb, G. Lukacs, E. A. Fon, J.-F. Trempe

The paper reports crystal structures of insect PINK1, revealing a dimeric autophosphorylation complex and insights into its binding to the TOM complex.

bioRxiv · Aug 5, 2021Biochemistry