Author

S. Siebel

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Physiology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:mouse· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Research Focus:metabolism & bioenergetics· 1 Organism:rat· 1

Frequent Co-Authors

A. Abulizi· 1 shared A. R. Nasiri· 1 shared A. Wang· 1 shared B. G. Costa Lima· 1 shared B. Wang· 1 shared C. Kung· 1 shared C. Thomas· 1 shared C. Yu· 1 shared

Activity by Year

2020-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperPhysiology

A. Abulizi

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2 papers

Recent·Most cited

GDF15 is a Critical Renostat in the Defense Against Hypoglycemia

Z. Li, X. Zhang, W. Zhu, Q. Xu, C. Yu, Q. Zhao, S. Siebel, C. Zhang, B. G. Costa Lima, X. Li, K. Israni-Winger, A. R. Nasiri, M. J. Caplan, R. B. Chang, A. Wang, , R. J. Perry

This study identifies GDF15 as a new hypoglycemia counterregulatory hormone, showing it increases hepatic gluconeogenesis through renal release and beta-adrenergic receptor-2 signaling.

bioRxiv · Jun 22, 2023 · PreprintPhysiology

Pharmacologic activation of the mitochondrial phosphoenolpyruvate cycleenhances islet function in vivo

A. Abulizi, R. Stark, R. L. Cardone, S. L. Lewandowski, X. Zhao, T. C. Alves, C. Thomas, C. Kung, B. Wang, S. Siebel, Z. B. Andrews, M. J. Merrins, R. G. Kibbey

This study shows that pharmacologic activation of pyruvate kinase (PK) enhances insulin secretion in preclinical diabetes models by stimulating the mitochondrial phosphoenolpyruvate (PEP) cycle.

bioRxiv · Feb 13, 2020 · PreprintPhysiology