Genome profiles of lymphovascular breast cancer cells reveal multiple clonally differentiated outcomes with multi-regional LCM and G&T-seq
Z. Zhu, W. Wang, F. Lin, T. Jordan, G. Li, S. Silverman, S. Qiu, A. A. Joy, C. Chen, D. Hockley, X. Zhang, Q. Zhou, L.-M. Postovit, X. Zhang, Y. Hou, , G. K.-S. Wong
This study isolates lymphovascular breast cancer cells using LCM and G&T-seq to identify three distinct clonal pathways associated with different survival outcomes and ribosomal protein downregulation as a poor prognosis marker.
bioRxiv · Feb 1, 2020Cancer Biology