Cancer BiologybioRxivPreprint
A non-canonical EZH2 function sensitizes solid tumors to genotoxic stress
Y. LIAO, C.-H. Chen, N. Shah…·K. Xu
This study shows EZH2 inhibitors inhibit CRPC growth by downregulating DNA repair genes, making cancer cells more sensitive to genotoxic stress.
DOI 10.1101/2020.09.11.291534