Author

T. Caspary

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 4 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 5 Research Focus:cell signaling & trafficking· 4 Research Focus:cell type annotation· 3 Organism:mouse· 3 Research Focus:development & morphogenesis· 2 Assay:proteomics· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:chromatin & epigenetic regulation· 1

Frequent Co-Authors

J. Linnert· 3 shared R. E. Turn· 3 shared U. Wolfrum· 3 shared K. R. Hardin· 2 shared R. A. Kahn· 2 shared S. I. Dewees· 2 shared A. B. Long· 1 shared A. Lee· 1 shared

Activity by Year

2021-2023 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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3 shared papersCell Biology

J. Linnert

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

GRK2 Kinases in the Primary Cilium Initiate SMOOTHENED-PKA Signaling in the Hedgehog Cascade

M. F. Walker, J. Zhang, W. Steiner, P.-I. Ku, J.-F. Zhu, Z. Michaelson, Y.-C. Yen, A. Lee, A. B. Long, M. J. Casey, A. Poddar, I. B. Nelson, C. D. Arveseth, F. Nagel, R. Clough, , B. R. Myers

This study identifies GRK2-mediated phosphorylation of SMO in the primary cilium as a critical step initiating SMO-PKA signaling in the Hedgehog pathway.

bioRxiv · May 10, 2023Cell Biology

Increasing Ciliary ARL13B Expression Drives Active and Inhibitor-Resistant SMO and GLI into Glioma Primary Cilia

P. Shi, J. Tian, J. Mallinger, L. Deleyrolle, J. McIntyre, T. Caspary, J. Breunig, M. R. Sarkisian

This study shows increased ARL13B expression drives active and inhibitor-resistant SMO and GLI into glioma cilia, promoting treatment resistance.

bioRxiv · Nov 28, 2022Cancer Biology

Phylogenetic profiling and cellular analyses of ARL16 reveal roles in traffic of IFT140 and INPP5E

S. I. Dewees, R. Vargova, K. R. Hardin, R. E. Turn, S. Devi, J. Linnert, U. Wolfrum, T. Caspary, M. Elias, R. Kahn

This study identifies ARL16's role in Golgi-to-cilium trafficking by showing its deletion causes accumulation of IFT140 and INPP5E at the Golgi in MEFs.

bioRxiv · Oct 14, 2021Cell Biology

The ARF GAPs ELMOD1 and ELMOD3 act at the Golgi and Cilia to Regulate Ciliogenesis and Ciliary Protein Traffic

R. E. Turn, Y. Hu, S. I. Dewees, N. Devi, M. P. East, K. R. Hardin, T. Khatib, J. Linnert, U. Wolfrum, J. Y. Lim, J. E. Casanova, T. Caspary, R. A. Kahn

This study identifies ELMOD1 and ELMOD3 as regulators of ciliogenesis and ciliary protein traffic, with phenotypes similar to ELMOD2 deletion but distinct in their effects on Golgi-ciliary transport.

bioRxiv · Sep 15, 2021Cell Biology

Roles for ELMOD2 and Rootletin in Ciliogenesis

R. E. Turn, J. Linnert, E. D. Gigante, U. Wolfrum, T. Caspary, R. A. Kahn

This study identifies ELMOD2 and Rootletin as regulators of ciliary licensing through their interaction with ARL2, maintaining centrosome cohesion and preventing spurious ciliation.

bioRxiv · Jan 4, 2021Cell Biology