A non-genetic model of vascular shunts informs on the cellular mechanisms of formation and resolution of arteriovenous malformations
M. Ouarne, A. Pena, D. Ramalho, N. Conchinha, T. Costa, A. Figueiredo, M. Saraiva, Y. Carvalho, L. Misikova, P. Oh, C. Franco
This study identifies EC volume changes as the key mechanism for AV shunt formation and regression, using a non-genetic model in mice.
bioRxiv · Aug 21, 2023Cell Biology