MicrobiologybioRxivPreprint
Structure-based design of a highly stable, covalently-linked SARS-CoV-2 spike trimer with improved structural properties and immunogenicity
E. Olmedillas, C. J. Mann, W. Peng…·E. Ollmann Saphire
This paper designs a modified SARS-CoV-2 spike trimer, VFLIP, with enhanced stability, immunogenicity, and structural fidelity to the native spike.
DOI 10.1101/2021.05.06.441046