Author

T. Hitosugi

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Assay:proteomics· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Organism:mouse· 1

Frequent Co-Authors

A. M. Saarinen· 1 shared C. Li· 1 shared D. A. Bernlohr· 1 shared H. Zeng· 1 shared J. A. Copland· 1 shared J. Liu· 1 shared J. Sun· 1 shared L. Wang· 1 shared

Activity by Year

2017-2020 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperBiochemistry

A. M. Saarinen

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2 papers

Recent·Most cited

ImmunologybioRxivApr 22, 2020

Stearoyl-CoA desaturase mediated monounsaturated fatty acid availability supports humoral immunity

X. Zhou, X. Zhu, C. Li…·H. Zeng

The paper shows that monounsaturated fatty acids (MUFA) are essential for B cell function and humoral immunity, with SCD-mediated MUFA production supporting early B cell development and germinal center formation.

DOI 10.1016/j.celrep.2020.108601

mouseproteomics

𝕏 PostBluesky

BiochemistryeLifePeer-reviewedDec 19, 2017

Inhibition of Intracellular Lipolysis Promotes Cancer Cell Adaptation to Hypoxia

X. Zhang, A. M. Saarinen, T. Hitosugi…·J. Liu

The paper shows that HIG2 inhibits ATGL to promote lipid droplet accumulation in hypoxic cancer cells, supporting their survival by reducing ROS and apoptosis.

DOI 10.7554/elife.31132

humanproteomics

𝕏 PostBluesky