T. O'Brien

The paper designs and validates an open-loop controlled positive-displacement pump for generating patient-specific vascular flow-rate waveforms, showing it approximates a linear first-order response with minimal impact on waveform realism.

This study compares MSC characteristics across three tissue sources using harmonised culture conditions, finding reproducible results and source-specific functional differences.

This paper introduces a high-resolution imaging system for tracking small animals in multiwell plates, enabling detailed behavioral analysis at scale.

The paper uses AFM-LS to correlate nuclear morphology and external force, revealing distinct roles of chromatin and lamin A/C in nuclear mechanics.

This study shows that preconditioning mesenchymal stem cells on a 3D microgel platform enhances angiogenesis in vivo at a low-cell dose by modulating extracellular stiffness and integrin signaling.