T. R. O'Meara

The paper uses imaging-based screening to identify compounds that inhibit hyphal transition in C. albicans, identifying eIF3 as a target of NSC 697923.

This paper describes a high-throughput screening method using human PBMCs to identify adjuvant candidates, resulting in a lead compound with in vivo adjuvanticity.

This study identifies 17 FDA-approved compounds with antiviral efficacy against SARS-CoV-2 using high-throughput screening and finds lactoferrin as a promising drug candidate with multiple antiviral mechanisms.

This study evaluates AH:CpG adjuvant's ability to enhance RBD vaccine efficacy in aged mice and human elder cells, showing strong neutralizing antibody responses and cytokine production.

This paper identifies genes regulating morphogenesis in Candida auris using forward and reverse genetic approaches and develops tools for efficient genetic manipulation.

This paper builds a co-expression network for Candida albicans using RNA-seq data to predict gene function and identifies CCJ1 as a novel cell cycle regulator.

This paper introduces a method to selectively induce O-GlcNAcylation on target proteins using nanobody-fused OGT, enabling precise study of O-GlcNAc modifications in cells.