Author

V. Bhardwaj

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 3 Biophysics· 1 Cell Biology· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 5 Research Focus:host-pathogen & immune response· 4 Organism:human· 4 Assay:proteomics· 4 Research Focus:chromatin & epigenetic regulation· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1

Frequent Co-Authors

A. Chande· 2 shared A. G. Smith· 2 shared A. Singh· 2 shared F. Bunbury· 2 shared N. Vijay· 2 shared A. Biran· 1 shared A. D. Badley· 1 shared A. Groth· 1 shared

Activity by Year

2017-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 9 mutual co-author links

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2 shared papersMicrobiology

A. Chande

Mutual co-authors in cluster

Author profile →

6 papers

Recent·Most cited

Acute multi-level response to defective de novo chromatin assembly in S-phase

J. Dreyer, G. Ricci, J. van den Berg, V. Bhardwaj, J. Funk, C. Armstrong, V. van Batenburg, C. Sine, M. A. Vaninsberghe, R. Marsman, I. K. Mandemaker, S. di Sanzo, J. Costantini, S. Manzo, A. Biran, , F. Mattiroli

This study investigates the acute effects of CAF-1 loss on chromatin assembly during S-phase, revealing multi-level responses including replication slowdown and histone modification changes.

bioRxiv · Mar 22, 2024Cell Biology

HIV-1 Vpr induces ciTRAN to prevent transcriptional silencing of the provirus

V. Bhardwaj, A. Singh, R. Dalavi, L. Ralte, R. L. Chawngthu, N. Senthil Kumar, N. Vijay, A. Chande

This study identifies ciTRAN, a circular RNA induced by HIV-1 Vpr that sequesters SRSF1 to enhance viral transcription.

bioRxiv · Nov 4, 2022Microbiology

Exploring the onset of B12-based mutualisms using a recently evolved Chlamydomonas auxotroph and B12-producing bacteria

F. Bunbury, E. Deery, A. Sayer, V. Bhardwaj, E. Harrison, M. J. Warren, A. G. Smith

The paper investigates how a B12-dependent alga forms mutualisms with B12-producing bacteria, finding that higher B12 release by bacteria benefits both partners in co-culture.

bioRxiv · Jan 4, 2022Microbiology

Secreted ORF8 is a pathogenic cause of severe Covid-19 and potentially targetable with select NLRP3 inhibitors

X. Wu, M. K. Manske, G. Ruan, T. L. Witter, K. E. Nowakowski, J. P. Abeykoon, X. Tang, Y. Yu, K. A. Gwin, A. Wu, V. Taupin, V. Bhardwaj, J. Paludo, S. Dasari, H. Dong, , T. E. Witzig

This study identifies ORF8 as a secreted glycoprotein that drives severe COVID-19 through NLRP3 inflammasome activation and shows it is inhibited by MCC950.

bioRxiv · Dec 2, 2021Immunology

Coevolution of retroviruses with SERINCs following whole-genome duplication divergence

P. Ramdas, V. Bhardwaj, A. Singh, N. Vijay, A. Chande

This study investigates the coevolution of retroviruses with SERINC proteins, showing functional conservation among SERINC paralogs and the role of whole-genome duplication in shaping anti-retroviral activity.

bioRxiv · Feb 24, 2020 · PreprintMicrobiology

Mutualism between microbial populations in structured environments: the role of geometry in diffusive exchanges

F. J. Peaudecerf, F. Bunbury, V. Bhardwaj, M. A. Bees, A. G. Smith, R. E. Goldstein, O. A. Croze

The paper models how geometric structure affects diffusive exchanges in microbial mutualisms, showing counterintuitive dependencies on diffusion geometry in a synthetic algal-bacterial co-culture.

bioRxiv · Oct 30, 2017Biophysics