Author

V. Gardeux

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 2 Cell Biology· 2 Immunology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 5 Research Focus:cell type annotation· 4 Assay:scRNA-seq· 4 Organism:human· 3 Organism:mouse· 3 Assay:bulk RNA-seq· 2 Research Focus:differential expression· 2 Research Focus:gene regulatory network inference· 2

Frequent Co-Authors

B. Deplancke· 6 shared J. Russeil· 5 shared J. Pezoldt· 4 shared D. Alpern· 3 shared M. Biocanin· 3 shared W. Saelens· 3 shared G. van Mierlo· 2 shared P. Rainer· 2 shared

Activity by Year

2019-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 40 mutual co-author links

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6 shared papersCell Biology

B. Deplancke

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6 papers

Recent·Most cited

Dissecting reprogramming heterogeneity at single-cell resolution using scTF-seq

W. Liu, W. Saelens, P. Rainer, M. Biocanin, V. Gardeux, A. Gralak, G. van Mierlo, J. Russeil, T. Liu, W. Chen, B. Deplancke

The paper introduces scTF-seq, a method to study TF dose-dependent reprogramming in mouse MSCs, revealing heterogeneity in cell fate and TF sensitivity.

bioRxiv · Jan 30, 2024Cell Biology

A human omentum-specific mesothelial-like stromal population inhibits adipogenesis through IGFBP2 secretion

R. Ferrero, P. Rainer, J. Russeil, M. Zachara, J. Pezoldt, G. van Mierlo, V. Gardeux, W. Saelens, D. Alpern, L. Favre, S. Mantziari, T. Zingg, N. Pitteloud, M. Suter, M. Matter, , B. Deplancke

The paper identifies an omental-specific stromal population that inhibits adipogenesis via IGFBP2 secretion in human adipose tissue.

bioRxiv · May 1, 2023Cell Biology

Postnatal lymph node expansion of stromal progenitors towards reticular and CD34+ stromal cell subsets is determined by distinct transcriptional programs

J. Pezoldt, C. Wiechers, M. Litovchenko, M. Biocanin, M. Zou, K. Sitnik, M. Beckstette, W. Chen, V. Gardeux, S. Floess, M. Ebel, J. Russeil, P. Arampatzi, E. Vafardanejad, A.-E. Saliba, , J. Huehn

The paper identifies distinct transcriptional programs driving the expansion of stromal progenitors in mesenteric lymph nodes, revealing Irf3's role in FRC differentiation and microbiota-independent epigenomic signatures.

bioRxiv · Jun 6, 2021 · PreprintImmunology

Deterministic scRNA-seq of individual intestinal organoids reveals new subtypes and coexisting distinct stem cell pools

J. Bues, M. Biocanin, J. Pezoldt, R. Dainese, A. Chrisnandy, S. Rezakhani, W. Saelens, V. Gardeux, R. Gupta, J. Russeil, Y. Saeys, E. Amstad, M. Claassen, M. Lutolf, B. Deplancke

The paper introduces DisCo, a deterministic scRNA-seq method for small tissue samples, revealing new intestinal organoid subtypes and stem cell populations.

bioRxiv · May 19, 2020 · PreprintBioengineering

Disparate temperature-dependent virus - host dynamics for SARS-CoV-2 and SARS-CoV in the human respiratory epithelium

P. V'kovski, M. Gultom, J. N. Kelly, S. Steiner, J. Russeil, B. Mangeat, E. Cora, J. Pezoldt, M. Holwerda, A. Kratzel, L. Laloli, M. Wider, J. Portmann, T. T. N. Thao, N. Ebert, , R. Dijkman

This study compares temperature-dependent replication and immune response dynamics of SARS-CoV-2 and SARS-CoV in human airway epithelial cells, highlighting differences in their antiviral responses and transmission efficiency.

bioRxiv · Apr 27, 2020Microbiology

A highly parallel, automated platform enabling individual or sequential ChIP of histone marks and transcription factors

R. Dainese, V. Gardeux, G. Llimos, D. Alpern, J. Y. Jiang, A. Meireles-Filho, B. Deplancke

This paper introduces FloChIP, a microfluidic platform for automated ChIP-seq that improves speed, throughput, and sensitivity compared to traditional methods.

bioRxiv · Aug 7, 2019Bioengineering