Author

M. Zou

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2 Plant Biology· 2 Immunology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 3 Assay:bulk RNA-seq· 2 Approach:deep learning· 2 Approach:experimental assay· 2 Organism:human· 2 Organism:mouse· 2 Assay:proteomics· 2 Approach:statistical model· 2

Frequent Co-Authors

A. Califano· 2 shared A. Vasciaveo· 2 shared C. Abate-Shen· 2 shared J. Friml· 2 shared L. Li· 2 shared M. A. Rubin· 2 shared M. M. Shen· 2 shared A. Mitrofanova· 1 shared

Activity by Year

2021-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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2 shared papersCancer Biology

A. Califano

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

NSD2 maintains lineage plasticity and castration-resistance in neuroendocrine prostate cancer

J. J. Li, A. Vasciaveo, D. Karagiannis, Z. Sun, X. Chen, F. Socciarelli, Z. Frankenstein, M. Zou, T. Pannellini, Y. Chen, K. Gardner, B. D. Robinson, J. de Bono, C. Abate-Shen, M. A. Rubin, , M. M. Shen

This study identifies NSD2 as a key driver of lineage plasticity and castration-resistance in neuroendocrine prostate cancer, showing its inhibition can restore sensitivity to AR inhibitors.

bioRxiv · Jul 18, 2023 · PreprintCancer Biology

Distinct functions of TIR1 and AFB1 receptors in auxin signalling

H. Chen, L. Li, M. Zou, L. Qi, J. Friml

The paper compares the roles of TIR1 and AFB1 in transcriptional and rapid auxin responses, showing their distinct functions are due to specific protein properties, not subcellular localization.

bioRxiv · Jan 5, 2023Plant Biology

ABP1/ABL3-TMK1 cell-surface auxin signaling directly targets PIN2-mediated auxin fluxes for root gravitropism

L. Rodriguez, L. Fiedler, M. Zou, C. Giannini, A. Monzer, D. Vladimirtsev, M. Randuch, Y. Yu, Z. Gelova, I. Verstraeten, J. Hajny, M. Chen, S. Tan, L. Hoermayer, L. Li, , J. Friml

The paper identifies a mechanism where auxin signaling via ABP1-TMK1 receptor module stabilizes PIN2 to reinforce asymmetric auxin flow for root gravitropism.

bioRxiv · Nov 30, 2022Plant Biology

OncoLoop: A network-based precision cancer medicine framework

A. Vasciaveo, M. Zou, J. M. Arriaga, F. Geraldes de Almeida, E. F. Douglass, M. Shibata, A. Rodriguez-Calero, S. de Brot, A. Mitrofanova, C. W. Chua, C. Karan, R. Realubit, S. Y. Pampou, J. Y. Kim, E. Corey, , C. Abate-Shen

OncoLoop predicts and validates drug sensitivity in tumors and their models by leveraging perturbational profiles of oncology drugs, showing success in prostate cancer models and patient cohorts.

bioRxiv · Feb 11, 2022Cancer Biology

Postnatal lymph node expansion of stromal progenitors towards reticular and CD34+ stromal cell subsets is determined by distinct transcriptional programs

J. Pezoldt, C. Wiechers, M. Litovchenko, M. Biocanin, M. Zou, K. Sitnik, M. Beckstette, W. Chen, V. Gardeux, S. Floess, M. Ebel, J. Russeil, P. Arampatzi, E. Vafardanejad, A.-E. Saliba, , J. Huehn

The paper identifies distinct transcriptional programs driving the expansion of stromal progenitors in mesenteric lymph nodes, revealing Irf3's role in FRC differentiation and microbiota-independent epigenomic signatures.

bioRxiv · Jun 6, 2021 · PreprintImmunology