Author

S. Steiner

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 8

Signature Assays, Organisms & Methods

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Approach:experimental assay· 7 Research Focus:host-pathogen & immune response· 5 Organism:human· 5 Organism:mouse· 3 Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 2 Research Focus:drug response / drug discovery· 2 Assay:imaging· 2

Frequent Co-Authors

N. Ebert· 6 shared R. Dijkman· 6 shared V. Thiel· 6 shared A. Kratzel· 5 shared H. Stalder· 5 shared T. T. N. Thao· 5 shared J. Portmann· 4 shared M. Holwerda· 4 shared

Activity by Year

2020-2023 · peak 5/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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Curved chords = mutual co-authorship

6 shared papersMicrobiology

N. Ebert

Mutual co-authors in cluster

Author profile →

8 papers

Recent·Most cited

Monkeypox virus spreads from cell-to-cell and leads to neuronal death in human neural organoids

I. Schultz-Pernice, A. Fahmi, F. Britto, M. Liniger, Y.-C. Chiu, T. David, B. I. Oliveira Esteves, A. Golomingi, B. Zumkehr, M. Gerber, D. Jandrasits, R. Zuest, S. Steiner, C. Wotzkow, F. Blank, , M. P. Alves

This study shows MPXV spreads cell-to-cell in human neural organoids, causing neuronal death and neuritic bead formation, and identifies tecovirimat as effective in reducing viral load.

bioRxiv · Sep 19, 2023Microbiology

Developmental transitions coordinate assembly of the Coxiella burnetii Dot/Icm type IV secretion system

D. Park, S. Steiner, M. Shao, C. Roy, J. Liu

This study uses cryo-ET to show that the Dot/Icm T4SS assembles during the transition from large to small cell variants in Coxiella burnetii.

bioRxiv · May 29, 2022Microbiology

The spike gene is a major determinant for the SARS-CoV-2 Omicron-BA.1 phenotype

T. Barut, N. J. Halwe, A. Taddeo, J. N. Kelly, J. Schön, N. Ebert, L. Ulrich, C. Devisme, S. Steiner, B. S. Trueeb, B. Hoffmann, I. B. Veiga, N. F. G. Leborgne, E. A. Moreira, A. Breithaupt, , V. Thiel

This study shows the spike gene determines replication, pathogenicity, and immune evasion of SARS-CoV-2 Omicron-BA.1 compared to Delta in cell cultures and animal models.

bioRxiv · Apr 28, 2022Microbiology

Susceptibility of well-differentiated airway epithelial cell cultures from domestic and wildlife animals to SARS-CoV-2

M. Gultom, M. Licheri, L. Laloli, M. Wider, M. Straessle, S. Steiner, A. Kratzel, T. T. N. Thao, H. Stalder, J. Portmann, M. Holwerda, P. V'kovski, N. Ebert, N. Stokar - Regenscheit, C. Gurtner, , R. Dijkman

This study assesses the susceptibility of airway epithelial cell cultures from various animals to SARS-CoV-2, finding efficient replication only in monkey and cat models.

bioRxiv · Nov 10, 2020 · PreprintMicrobiology

SARS-CoV-2 spike D614G variant confers enhanced replication and transmissibility

B. Zhou, T. T. N. Thao, D. Hoffmann, A. Taddeo, N. Ebert, F. Labroussaa, A. Pohlmann, J. King, J. Portmann, N. J. Halwe, L. Ulrich, B. S. Trueb, J. N. Kelly, X. Fan, B. Hoffmann, , M. Beer

This study shows the SARS-CoV-2 D614G variant has enhanced replication and transmissibility in animal models, explaining its global dominance.

bioRxiv · Oct 27, 2020Microbiology

Disparate temperature-dependent virus - host dynamics for SARS-CoV-2 and SARS-CoV in the human respiratory epithelium

P. V'kovski, M. Gultom, J. N. Kelly, S. Steiner, J. Russeil, B. Mangeat, E. Cora, J. Pezoldt, M. Holwerda, A. Kratzel, L. Laloli, M. Wider, J. Portmann, T. T. N. Thao, N. Ebert, , R. Dijkman

This study compares temperature-dependent replication and immune response dynamics of SARS-CoV-2 and SARS-CoV in human airway epithelial cells, highlighting differences in their antiviral responses and transmission efficiency.

bioRxiv · Apr 27, 2020Microbiology

Efficient inactivation of SARS-CoV-2 by WHO-recommended hand rub formulations and alcohols

A. Kratzel, D. Todt, P. V'kovski, S. Steiner, M. L. Gultom, T. T. N. Thao, N. Ebert, M. Holwerda, J. Steinmann, D. Niemeyer, R. Dijkman, G. Kampf, C. Drosten, E. Steinmann, V. Thiel, S. Pfaender

The paper tests the virucidal activity of WHO-recommended hand rubs and alcohols against SARS-CoV-2, showing efficient inactivation for all tested products.

bioRxiv · Mar 10, 2020 · PreprintMicrobiology

Rapid reconstruction of SARS-CoV-2 using a synthetic genomics platform

T. T. N. Thao, F. Labroussaa, N. Ebert, P. V'kovski, H. Stalder, J. Portmann, J. Kelly, S. Steiner, M. Holwerda, A. Kratzel, M. Gultom, L. Laloli, L. Huesser, M. Wider, S. Pfaender, , V. Thiel

This paper describes a yeast-based synthetic genomics platform for rapid reconstruction of RNA viruses, including SARS-CoV-2, using synthetic DNA fragments and TAR cloning.

bioRxiv · Feb 21, 2020Microbiology