Apolipoprotein E O-glycosylation is associated with amyloid plaques and APOE genotype.
P. E. Lawler, J. G. Bollinger, S. E. Schindler, C. R. Hodge, N. J. Iglesias, V. Krishnan, J. B. Coulton, Y. Li, D. M. Holtzman, R. J. Bateman
The paper quantifies apoE glycosylation in plasma and CSF, finding associations with APOE genotype, total apoE levels, and amyloid status in older individuals.
bioRxiv · Jan 3, 2023 · PreprintBiochemistry