A Mechanistic Study on the Cellular Uptake, Intracellular Trafficking, and Antisense Gene Regulation of Bottlebrush Polymer-Conjugated Oligonucleotides
L. Zhang, Y. Wang, P. Chen, D. Wang, Z. Zhang, W. Ruimeng, X. Kang, Y. Fang, H. Lu, J. Cai, M. Ren, S. Dong, K. Zhang
This paper investigates the cellular uptake, trafficking, and antisense gene regulation mechanisms of bottlebrush polymer-conjugated oligonucleotides in cancer cells.
bioRxiv · Jun 15, 2022Bioengineering