Author

W.-J. Li

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 4 Cell Biology· 2 Evolutionary Biology· 2 Bioengineering· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 5 Assay:metagenomics· 4 Approach:statistical model· 4 Research Focus:phylogenetics / evolution· 3 Research Focus:cell signaling & trafficking· 2 Research Focus:cell type annotation· 2 Research Focus:host-pathogen & immune response· 2 Assay:proteomics· 2

Frequent Co-Authors

L.-X. Chen· 3 shared B. Al-Shayeb· 2 shared J. A. Doudna· 2 shared J. F. Banfield· 2 shared R. Meheust· 2 shared R.-K. Zhang· 2 shared Y.-X. Liu· 2 shared Z.-C. Fan· 2 shared

Activity by Year

2018-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 19 mutual co-author links

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3 shared papersMicrobiology

L.-X. Chen

Mutual co-authors in cluster

Author profile →

9 papers

Recent·Most cited

Autologous iPSC- and MSC-derived Chondrocyte Implants for Cartilage Repair in a Miniature Pig Model

M.-S. Lee, A. Sivapatham, E. M. Leiferman, H. Jiao, Y. Lu, B. W. Nemke, M. Leiferman, M. D. Markel, W.-J. Li

This study compares autologous iPSC- and BMSC-derived chondrocyte implants in minipigs, finding iMSC-Ch implants produce more hyaline cartilage-like tissue.

bioRxiv · Jul 25, 2023Bioengineering

Inference and reconstruction of the heimdallarchaeial ancestry of eukaryotes

L. Eme, D. Tamarit, E. F. Caceres, C. Stairs, V. de Anda, M.-E. Schon, K. Seitz, N. Dombrowski, W. H. Lewis, J. H. Saw, F. Homa, J. Lombard, T. Nunoura, W.-J. Li, Z.-S. Hua, , T. J. G. Ettema

The paper reconstructs the evolutionary ancestry of eukaryotes by analyzing Asgard archaea phylogenetic data and infers the last common ancestor of Asgard archaea and eukaryotes as a thermophilic chemolithotroph.

bioRxiv · Mar 7, 2023Evolutionary Biology

Metagenomic discovery of Candidatus Parvarchaeales related lineages sheds light on the adaptation and diversification from neutral-thermal to acidic-mesothermal environments

Y.-z. Rao, Y.-x. Li, Z.-w. Li, Y. Qu, Y.-L. Qi, J.-Y. Jiao, W. Shu, Z.-S. Hua, W.-J. Li

This paper identifies new Parvarchaeales lineages through metagenomics and reveals their adaptation strategies to extreme environments via genomic and metabolic analysis.

bioRxiv · Dec 14, 2022 · PreprintMicrobiology

Unraveling the Intricate Cargo-BBSome Coupling Mechanism at the Ciliary Tip

Y.-X. Liu, W.-J. Li, R.-K. Zhang, S.-N. Sun, Z.-C. Fan

This paper elucidates the mechanism by which ARL13 and BBS3 mediate cargo-BBSome coupling at the ciliary tip through a GTPase cycle and BBS3-dependent nucleotide exchange.

bioRxiv · Nov 2, 2022 · PreprintCell Biology

ARL3 Mediates BBSome Ciliary Turnover by Promoting Its Outward Diffusion through the Transition Zone

Y.-X. Liu, W.-Y. Sun, B. Xue, R.-K. Zhang, W.-J. Li, X. Xie, Z.-C. Fan

bioRxiv · Nov 19, 2021Cell Biology

Genomic Evidence for the Chinese Mountain Cat as a Wildcat Conspecific (Felis silvestris bieti) and Its Introgression to Domestic Cats

H. Yu, Y.-T. Xing, H. Meng, B. He, W.-J. Li, X.-Z. Qi, J.-Y. Zhao, Y. Zhuang, X. Xu, S. J. O'Brien, S.-J. Luo

The paper uses genomic data to classify the Chinese mountain cat as a wildcat subspecies and finds no evidence of its role in domestic cat domestication in East Asia.

bioRxiv · Dec 7, 2020Evolutionary Biology

Identification of 2019-nCoV related coronaviruses in Malayan pangolins in southern China

T. T.-Y. Lam, M. H.-H. Shum, H.-C. Zhu, Y.-G. Tong, X.-B. Ni, Y.-S. Liao, W. Wei, W. Y.-M. Cheung, W.-J. Li, L.-F. Li, G. M. Leung, E. C. Holmes, Y.-L. Hu, Y. Guan

The paper identifies 2019-nCoV related coronaviruses in Malayan pangolins, suggesting they may be intermediate hosts for the virus.

bioRxiv · Feb 13, 2020Microbiology

Clades of huge phage from across Earth’s ecosystems

B. Al-Shayeb, R. Sachdeva, L.-X. Chen, F. Ward, P. Munk, A. Devoto, C. J. Castelle, M. R. Olm, K. Bouma-Gregson, Y. Amano, C. He, R. Meheust, B. Brooks, A. Thomas, A. Lavy, , J. F. Banfield

The paper identifies major clades of large phage genomes across diverse ecosystems and highlights their expanded genetic repertoires and potential functional roles.

bioRxiv · Mar 11, 2019Microbiology

Candidate Phyla Radiation Roizmanbacteria from hot springs have novel, unexpectedly abundant, and potentially alternatively functioning CRISPR-Cas systems

L.-X. Chen, B. Al-Shayeb, R. Meheust, W.-J. Li, J. A. Doudna, J. F. Banfield

The paper identifies novel CRISPR-Cas systems in Roizmanbacteria from hot springs, including CasY and type I-B/III-A systems, and reports phage genomes associated with these systems.

bioRxiv · Nov 2, 2018Microbiology