Author
The University of Texas Medical Branch at GalvestonORCID 0000-0001-5553-1616Unclaimed ORCID profile · follow to get notified of new preprints
8 papers
Recent·Most cited
Yan Wang, Yanping Hu, Zhenhang Chen…·Xuping Xie
The paper analyzes the functional and structural characteristics of the SARS-CoV-2 BA.3.2.1 spike, showing trade-offs between immune evasion and replication fitness.
Adil Muneer, Ling Xie, Xuping Xie…·Xian Chen
This paper identifies G9a's role in SARS-CoV-2-induced pathogenesis by regulating translation of viral and host proteins, showing that G9a inhibitors can reverse disease-related proteomic changes.
Yan Wang, Long Sun, Luciana de Souza Fernandes…·Xuping Xie
This study identifies how NITD-688 inhibits dengue virus by binding NS4B and disrupting its interaction with NS3, reducing viral replication.
María González-Orozco, Tseng Hsiang-Chi, Adam Hage…·Ricardo Rajsbaum
This study identifies TRIM7 as an E3-ubiquitin ligase that ubiquitinates SARS-CoV-2 M protein to inhibit apoptosis and viral replication.
Ankita Singh, Awadalkareem Adam, Aditi Aditi…·Tian Wang
This study uses a murine model to investigate persistent neurological symptoms after SARS-CoV-2 Delta variant infection, finding long-term immune activation and behavioral abnormalities.
Lijing Zhang, Xuping Xie, Hannan Luo…·Qi Hu
This study identifies two double mutations in SARS-CoV-2 3CLpro that confer resistance to the non-covalent inhibitor WU-04 and reveals trade-offs between catalytic activity, thermostability, and drug resistance.
Jin Wang, Bing Liang Alvin Chew, Yong Lai…·Peter C. Dedon
The paper introduces CapQuant, a mass spectrometry-based method to analyze RNA caps, revealing new cap structures and variations in humans and mice.