Brenita C. Jenkins

This study investigates age-related mitochondrial structural deficits in the kidney, finding that the MICOS complex is impaired, leading to increased oxidative stress and mitochondrial dysfunction.

This study identifies microbial-specific Trp metabolism signatures in colitis by analyzing metabolites across multiple compartments in mice treated with DSS and antibiotics.

This study shows that inhibiting IDO1 restores hippocampal glucose metabolism and rescues cognition in Alzheimer's disease models.

This study investigates age-related changes in mitochondrial structure and function in the liver, identifying MICOS complex dysregulation as a contributor to metabolic and structural impairments.

This study shows that NMN supplementation in aged mice increases kidney inflammation and uremic toxins, suggesting age-specific risks of NAD+ boosting supplements.

This study identifies structural and metabolic changes in human heart failure using SBF-SEM and metabolomic analyses.