Xiumin Yan

This study uses super-resolution imaging to show that IFT complexes in C. elegans cilia dynamically dissociate with age, leading to reduced IFT velocity and ciliary dysfunction.

The paper identifies TRiC/CCT as a chaperonin in mammalian sperm flagella that folds locally translated proteins, supporting flagellar function and fertility.

This study identifies distinct roles of Kif6 and Kif9 in mammalian ciliary trafficking and motility, showing Kif6 is a motile cilia-specific IFT motor while Kif9 regulates the central apparatus.