Author

Kirstan Gimse

University of Wisconsin–MadisonORCID 0000-0002-3548-3634Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Neuroscience· 2 Bioengineering· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 2 Approach:experimental assay· 2 Organism:mouse· 2 Research Focus:cell type annotation· 1 Assay:CRISPR screen· 1 Approach:genetic perturbation / CRISPR· 1 Organism:human· 1

Frequent Co-Authors

Krishanu SahaiD· 3 shared Subhojit RoyiD· 2 shared Anjon AudhyaiD· 1 shared Brent D. AulstoniD· 1 shared Brittany Russell· 1 shared Cathleen M. LutziD· 1 shared Christian M. CapitiniiD· 1 shared Daniel Maldonado· 1 shared

Activity by Year

2023-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 22 mutual co-author links

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3 shared papersNeuroscience

Krishanu SahaORCID

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3 papers

Recent·Most cited

BioengineeringMolecular TherapyPeer-reviewedJan 14, 2025

Virus-free CRISPR knock-in of a chimeric antigen receptor into KLRC1 generates potent GD2-specific natural killer cells

Keerthana Shankar, Isabelle Zingler-Hoslet, Diana Marcela Tabima…·Krishanu Saha

This study uses CRISPR to disrupt an inhibitory receptor in NK cells and insert a GD2-targeting CAR, creating potent NK cells against GD2+ melanoma.

23 citationstop 2%

humangenetic perturbation / CRISPR

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NeurosciencebioRxivPreprintJun 8, 2024

Long term rescue of Alzheimer deficits in vivo by one-time gene-editing of App C-terminus.

Brent D. Aulston, Kirstan Gimse, Hannah Bazick…·Subhojit Roy

The paper uses CRISPR-Cas9 to edit the App gene in mice, reducing Alzheimer's disease symptoms and showing long-term benefits.

3 citations

mouseexperimental assay

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NeuroscienceBiomaterialsPeer-reviewedFeb 1, 2023

Efficient in vivo neuronal genome editing in the mouse brain using nanocapsules containing CRISPR-Cas9 ribonucleoproteins

Jeanette M. Metzger, Yuyuan Wang, Samuel S. Neuman…·Shaoqin Gong

This study develops non-viral nanocapsules for in vivo CRISPR-Cas9 delivery to edit neuronal DNA in mice, achieving efficient and safe genome editing in specific neuron types.

34 citations

mouseCRISPR screen

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