Author

Giuseppe Cannone

MRC Laboratory of Molecular BiologyORCID 0000-0002-4381-2522Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biochemistry· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Assay:cryo-EM· 1 Research Focus:drug response / drug discovery· 1 Research Focus:host-pathogen & immune response· 1 Assay:imaging· 1

Frequent Co-Authors

Abhay KotechaiD· 1 shared Ália dos SantosiD· 1 shared Alister BurtiD· 1 shared Amadeu LlebariaiD· 1 shared Aurélien FouilleniD· 1 shared Cyril GoudetiD· 1 shared David BarfordiD· 1 shared Dom BelliniiD· 1 shared

Activity by Year

2024-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperBiochemistry

Abhay KotechaORCID

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2 papers

Recent·Most cited

BiochemistryNature CommunicationsPeer-reviewedJan 13, 2025

Conformational diversity in class C GPCR positive allosteric modulation

Giuseppe Cannone, Ludovic Berto, Fanny Malhaire…·Guillaume Lebon

This study reports cryoEM structures of mGlu5 receptor with different PAMs, showing how PAM binding modulates receptor conformation and function.

17 citations

𝕏 PostBluesky

Cell BiologybioRxivPreprintOct 30, 2024

Human spermatogenesis leads to a reduced nuclear pore structure and function

Ália dos Santos, Oliver Knowles, Tom Dendooven…·Matteo Allegretti

This study investigates the structural and functional changes in human sperm nuclear pore complexes (NPCs) during spermatogenesis, revealing a reduced central channel and altered transport dynamics.

10 citations

𝕏 PostBluesky