Aminopeptidase N is a receptor for hedgehog merbecoviruses
Min Jin, Victoria A. Jefferson, Zhe Zhao…·Michael C. Letko
This study identifies Aminopeptidase N as the receptor for hedgehog merbecoviruses and shows restricted cross-species receptor use.
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Yale UniversityORCID 0000-0003-3520-2422Unclaimed ORCID profile · follow to get notified of new preprints
3 papers
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Min Jin, Victoria A. Jefferson, Zhe Zhao…·Michael C. Letko
This study identifies Aminopeptidase N as the receptor for hedgehog merbecoviruses and shows restricted cross-species receptor use.
Mia Madel Alfajaro, Emma L. Keeler, Ning Li…·Craig B. Wilen
This study identifies bat and mink ACE2 as receptors for HKU5 merbecovirus, revealing distinct receptor interactions and highlighting mustelids as potential intermediate hosts.
Jonathan D. Lee, Bridget L. Menasché, Maria Mavrikaki…·Frank John Slack
This study shows that SARS-CoV-2 variants differ in syncytia formation, which affects host chromatin accessibility, cellular senescence, and inflammation via TP53.