Beth M. Stadtmueller

This study shows that IgA suppresses epithelial proliferation and tumorigenesis by interacting with DMBT1, highlighting its role in maintaining mucosal homeostasis.

This study characterizes the structural evolution of Fcα/μR-mediated antibody recognition across vertebrates by analyzing duck and mouse Fc/R interactions with IgM and IgA.

This study characterizes antibody responses to H3 influenza A virus in mallard ducks, revealing unique features compared to human antibodies and highlighting gene conversion in antibody evolution.

The paper reports cryo-EM structures of avian IgA and compares them to mammalian IgA, revealing structural differences that may affect mucosal immune responses.

The paper reports cryo-EM structures of chimeric and human IgM, revealing structural insights into JC-free pIgM assembly and demonstrating antigen-targeting potential for disease prevention.

This study identifies key residues in secretory component domains D1 and D3 and JC C-terminal residues that mediate binding to dIgA and stabilize SIgA structure.

This study engineers chimeric SIgA to investigate and enhance effector mechanisms against C. difficile, showing increased neutralization and bacterial clumping.