Chang Liu

This study uses β-barrel domain swapping to engineer α-hemolysin nanopores with enhanced single-molecule sensing capabilities.

The paper reprocesses SARS-CoV-2 genomic data to correct systematic errors in phylogenies using a novel assembly tool, resulting in a cleaner global tree of 4.47 million samples.

This study shows KCNQ1 regulates human neuronal development by affecting cell adhesion, mitochondrial function, and insulin signalling pathways.

The paper compares SARS-CoV-2 antigenicity across assays and in human and animal model sera, finding similar immunodominance patterns and antigenic maps but differences in titer magnitude and assay-specific fold change.

The paper investigates how multivalent interactions between SARS-CoV-2 spike protein, ACE2 receptor, and patient-derived antibodies influence viral entry and antibody inhibition.

This paper develops a bivalent binding model to analyze how molecular reach affects SARS-CoV-2 neutralization potency across antibodies.

The paper identifies mutations in SARS-CoV-2 variants that confer resistance to monoclonal antibodies by analyzing genomic data and validating their impact on antibody neutralization.