Author

A. Angione

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Research Focus:cancer & tumor microenvironment· 2 Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Organism:mouse· 2 Research Focus:cell signaling & trafficking· 1 Organism:human· 1 Approach:statistical model· 1

Frequent Co-Authors

A. C. Tarbay· 1 shared A. Cillo· 1 shared A. Duensing· 1 shared A. Li· 1 shared A. M. Tsankov· 1 shared A. N. Mallela· 1 shared A. Rao· 1 shared A. Venketeswaran· 1 shared

Activity by Year

2022-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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1 shared paperCancer Biology

A. C. Tarbay

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

All-trans retinoic acid induces durable tumor immunity in IDH-mutant gliomas by rescuing transcriptional repression of the CRBP1-retinoic acid axis

A. Rao, X. Zhang, A. Cillo, J. H. Sussman, P. Sandlesh, A. C. Tarbay, A. N. Mallela, C. Cardello, K. Krueger, J. Xu, A. Li, J. Xu, J. Patterson, E. Akca, A. Angione, , N. M. Amankulor

This study shows that all-trans retinoic acid (ATRA) improves immune response in IDH-mutant gliomas by restoring the RA pathway, leading to tumor regression in mouse models and a clinical trial for human patients.

bioRxiv · Apr 9, 2024 · PreprintCancer Biology

A paracrine circuit of IL-1b/IL-1R1 between myeloid and tumor cells drives glioblastoma progression

Z. Chen, B. Giotti, M. Kaluzova, C. Herting, G. Pinero, m. p. vallcorba, S. Cristea, J. L. Ross, J. Ackley, V. Maximov, F. Szulzewsky, M. Marquez-Ropero, A. Angione, N. Nichols, N. Tsankkova, , D. Hambardzumyan

The paper identifies a paracrine IL-1β/IL-1R1 circuit between myeloid and tumor cells that drives glioblastoma progression and shows that antagonizing this circuit reduces tumor growth and extends survival.

bioRxiv · Apr 3, 2022 · PreprintCancer Biology