A. Godzik

Global atlas of predicted functional domains in Legionella pneumophila Dot/Icm translocated effectors

The paper provides a global atlas of predicted functional domains in Legionella pneumophila effectors using 3D structure prediction, identifying novel domains and demonstrating their functional impact.

Sexual dimorphism in obesity is governed by RELMα regulation of adipose macrophages and eosinophils

This study identifies RELMα's role in sex-specific obesity protection by regulating adipose macrophages and eosinophils, revealing a therapeutic target for obesity.

Increased frequency of recurrent in-frame deletions in new expanding lineages of SARS CoV-2 reflects immune selective pressure

The paper identifies an increase in in-frame deletions in SARS-CoV-2 lineages, suggesting immune selective pressure as a driving force.

Microbial function and genital inflammation in young South African women at high risk of HIV infection

This study uses metaproteomics to link microbial function and inflammation in the female genital tract of South African women at high HIV risk, finding that reduced cell wall organization and peptidoglycan biosynthesis are associated with high inflammation.

The interplay of SARS-CoV-2 evolution and constraints imposed by the structure and functionality of its proteins

The paper analyzes SARS-CoV-2 mutations in relation to protein structure and function, finding that foldability and functional conservation drive evolutionary patterns.

The crystal structure of nsp10-nsp16 heterodimer from SARS CoV-2 in complex with S-adenosylmethionine

The paper determines the crystal structure of the SARS-CoV-2 nsp10-nsp16 heterodimer complex with S-adenosylmethionine at 1.80 Å resolution, revealing its role in viral mRNA capping and immune evasion.

Large scale analysis of smoking-induced changes in the tumor immune microenvironment

This study analyzes smoking-induced changes in the tumor immune microenvironment across ten cancer types using TCGA data, finding increased plasma cells and altered immune cell ratios linked to survival outcomes, with stronger effects in female smokers.

The functional impact of alternative splicing in cancer

The paper analyzes alternative splicing changes in cancer samples to identify their functional impact and potential role in tumorigenesis, finding a negative correlation with somatic mutations and proposing some as oncogenic processes.