A. Hay

Biological and Genetic Determinants of Glycolysis: Phosphofructokinase Isoforms Boost Energy Status of Stored Red Blood Cells and Transfusion Outcomes

The paper identifies genetic polymorphisms and metabolite levels in stored red blood cells that correlate with hemolysis and transfusion outcomes.

Ferroptosis regulates hemolysis in stored murine and human red blood cells

This study identifies Steap3 as a regulator of ferroptosis-like lipid peroxidation in stored RBCs, linking genetic variants to hemolysis in mice and human blood donors.

Amphicarpic development in the emerging model organism Cardamine chenopodiifolia

This paper establishes Cardamine chenopodiifolia as a model system for studying amphicarpy, identifying differentially expressed genes and developmental differences between above- and below-ground fruits.

Polyploid genome assembly of Cardamine chenopodiifolia

This paper presents a chromosome-scale genome assembly for the polyploid, amphicarpic plant Cardamine chenopodiifolia using long-read sequencing.

Growth and tension in explosive fruit

The paper investigates how tension in exploding seed pods of Cardamine hirsuta is generated through active cell growth and microtubule-controlled cellulose microfibril orientation.

Explosive seed dispersal depends on SPL7 to ensure sufficient copper for localized lignin deposition via laccases

The paper identifies SPL7 as essential for copper accumulation in Arabidopsis relative fruit valves, enabling laccase activity required for asymmetric lignin deposition and explosive seed dispersal.

INDEHISCENT regulates explosive seed dispersal

This study identifies INDEHISCENT as a key regulator of explosive seed dispersal in Cardamine hirsuta and shows developmental system drift in gene network function between C. hirsuta and Arabidopsis thaliana.

Mitophagy antagonism by Zika virus reveals Ajuba as a regulator of PINK1-Parkin signaling, PKR-dependent inflammation, and viral invasion of tissues.

This study shows ZIKV NS5 inhibits mitophagy by blocking Ajuba's role in PINK1-Parkin signaling, leading to increased inflammation and viral spread.

The interactome of the N-terminus of band 3 regulates red blood cell metabolism and storage quality

This paper investigates the role of the N-terminus of band 3 in red blood cell metabolism and storage quality using genetic models and proteomic analyses, showing its impact on metabolic pathways and transfusion outcomes.

Fine-scale ecological and transcriptomic data reveal niche differentiation of an allopolyploid from diploid parents in Cardamine

This study examines the ecological and transcriptomic differences between an allopolyploid plant and its diploid parents, finding niche differentiation linked to water availability.

A recently formed triploid Cardamine insueta inherits leaf vivipary and submergence tolerance traits of parents

This study characterizes the transcriptomic response of a recently formed triploid plant species to submergence, revealing inherited traits from its parental species.