A. Iglic

A minimal physical model for curvotaxis driven by curved protein complexes at the cell's leading edge

This paper develops a minimal physical model to explain curvotaxis by simulating curved protein complexes at the cell's leading edge and shows it matches experimental observations on curved substrates.

Modelling how curved active proteins and shear flow pattern cellular shape and motility

The paper models how curved active proteins and shear flow influence cellular shape and motility, showing cells reorient to minimize adhesion energy.

Theoretical model of membrane protrusions driven by curved active proteins

The paper extends a physical model of membrane protrusions driven by curved active proteins to explore the formation of different protrusive structures like lamellipodia and filopodia.

Theoretical model of efficient phagocytosis driven by curved membrane proteins and active cytoskeleton forces

This paper presents a theoretical model explaining how curved membrane proteins and active cytoskeletal forces drive efficient phagocytosis, showing reduced adhesion strength requirements and faster engulfment.

Modelling cellular spreading and emergence of motility in the presence of curved membrane proteins and active cytoskeleton forces

The paper models cellular spreading and motility by simulating vesicle behavior with curved membrane proteins and active forces, showing how these factors drive lamellipodia formation and motility.

Cell confinement reveals a branched-actin independent circuit for neutrophil polarity

This study shows that neutrophils can maintain polarity and movement without branched actin networks when confined, revealing a bleb-based protrusion mechanism distinct from the conventional actin-based one.