Targeting endothelial FOXO1 protects diabetic β-cells and improves wound healing
H. Wu, K. Cui, B. Zhu, Y. W. Lu, L. Sun, Q. Ma, A. Jian, D. O. Hurtado, X. Gao, Y. Li, S. Bhattacharjee, H. Fu, A. E. Birsner, M. Malovichko, M. Li, , H. Chen
This study shows that targeting endothelial FOXO1 reduces IGF2 levels, improves β-cell function, and enhances wound healing in diabetes.
bioRxiv · Dec 4, 2023 · PreprintCell Biology