Native doublet microtubules from Tetrahymena thermophila reveal the importance of outer junction proteins
S. Kubo, C. S. Black, E. Joachimiak, S. K. Yang, T. Legal, K. Peri, A. Khalifa, A. G. Miandoab, M. Valente, C. de Bellis, P. Huynh, Z. Fan, D. Wloga, K. H. Bui
The paper uses cryo-EM to analyze native doublet microtubules in Tetrahymena thermophila, identifying MIPs and showing their role in cilia function through CFAP77 knockout.
bioRxiv · Sep 30, 2022Biophysics