Author

A. Kung

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 3 Biochemistry· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:human· 3 Research Focus:drug response / drug discovery· 2 Organism:bacteria (other)· 1 Assay:bulk RNA-seq· 1 Research Focus:clustering· 1 Approach:deep learning· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

F. Dela Cruz· 2 shared A. Califano· 1 shared A. Henssen· 1 shared A. Kentsis· 1 shared A. Obradovic· 1 shared A. Schmidt· 1 shared A. Tannenbaum· 1 shared B. V. Kabasakal· 1 shared

Activity by Year

2017-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 10 mutual co-author links

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2 shared papersCancer Biology

F. Dela Cruz

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

The crystal structure of the Shethna Protein II (FeSII) from Azotobacter vinelandii suggests a domain swap

B. V. Kabasakal, C. R. McFarlane, C. A. Cotton, A. Schmidt, A. Kung, L. Lieber, J. W. Murray

The paper reinterprets the crystal structure of FeSII from Azotobacter vinelandii, proposing a domain swap rather than an open conformation due to oxidation state.

bioRxiv · Jan 30, 2024 · PreprintBiochemistry

Case Study of Single-cell Protein Activity Based Drug Prediction for Precision Treatment of Cholangiocarcinoma

A. Obradovic, L. Tomassoni, D. Yu, K. Guillan, K. Souto, E. Fraser, S. Bates, C. G. Drake, Y. Saenger, F. D. Cruz, A. Kung, A. Califano

The paper develops a single-cell framework to prioritize drugs for cholangiocarcinoma by analyzing subpopulations and validating predictions in patient-derived xenografts.

bioRxiv · Feb 28, 2022 · PreprintCancer Biology

Direct-from-specimen microbial growth inhibition spectrums under antibiotic exposure and comparison to conventional antimicrobial susceptibility testing

J. Chen, S. S. S. San, A. Kung, M. Tomasek, D. Liu, W. Rodgers, V. Gau

The paper introduces a rapid antimicrobial efficacy profiling method using clinical urine specimens, achieving 100% agreement with conventional AST methods for specific antibiotics.

bioRxiv · Feb 12, 2021Microbiology

Therapeutic targeting of PGBD5-induced DNA repair dependency in pediatric solid tumors

A. Henssen, C. Reed, E. Jiang, H. D. Garcia, J. von Stebut, I. MacArthur, P. Hundsdoerfer, J. Hyun Kim, E. de Stanchina, Y. Kuwahara, H. Hosoi, N. Ganem, F. Dela Cruz, A. Kung, J. Schulte, , A. Kentsis

This study identifies PGBD5 as a therapeutic target in pediatric solid tumors, showing that inhibiting DNA repair pathways with AZD6738 sensitizes these tumors to apoptosis.

bioRxiv · Aug 25, 2017Cancer Biology

Pediatric Sarcoma Data Forms a Unique Cluster Measured via the Earth Mover’s Distance

Y. Chen, F. Dela Cruz, R. Sandhu, A. Kung, P. Mundi, J. Deasy, A. Tannenbaum

The paper clusters pediatric and adult sarcoma data using optimal transport theory and identifies a unique pediatric cluster.

bioRxiv · Mar 13, 2017Cancer Biology