A. L. Marsden

High Shear Stress Reduces ERG Causing Endothelial-Mesenchymal Transition and Pulmonary Arterial Hypertension

The paper shows high shear stress induces endothelial-mesenchymal transition and pulmonary arterial hypertension by reducing ERG expression, which can be mitigated by ERG replenishment.

Longitudinal Investigation of Aortic Dissection in Mice with Computational Fluid Dynamics

This study uses computational fluid dynamics to analyze false lumen thrombus formation in mice with aortic dissection, finding that flow stagnation correlates with increased thrombus ratio and endothelial activation.

A Computational Growth and Remodeling Framework for Adaptive and Maladaptive Pulmonary Arterial Hemodynamics

This paper develops a computational framework to simulate adaptive and maladaptive pulmonary arterial hemodynamics and identify contributors to PAH phenotypes.

Hemodynamics in Patients with Aortic Coarctation: A Comparison of in vivo 4D-Flow MRI and FSI Simulation

This study compares in vivo 4D-Flow MRI and FSI simulations in patients with aortic coarctation to assess their agreement in quantifying hemodynamics.

Blood flow modeling reveals improved collateral artery performance during mammalian heart regeneration

This study uses computational modeling to show neonatal collateral arteries are more effective than adult ones in restoring blood flow during heart regeneration.

Computational Simulations of the 4-D Micro-Circulatory Network in Zebrafish Tail Amputation and Regeneration

This study uses computational fluid dynamics to model microvascular changes in zebrafish tail regeneration, showing dynamic shifts in wall shear stress and flow rate during vascular remodeling.