M. Rabinovitch

This study shows that frataxin deficiency in endothelial cells causes mitochondrial respiration defects and vasoconstriction, contributing to pulmonary hypertension.

This paper develops a computational framework to simulate adaptive and maladaptive pulmonary arterial hemodynamics and identify contributors to PAH phenotypes.

The paper maps immune cell subsets in PAH lungs using MIBI-TOF, identifying mo-DCs and their role in vascular remodeling and linking immune dysregulation to disease severity in HPAH.

This study identifies SUMOylation inhibition as a mechanism by which Leishmania amazonensis enhances its survival in host macrophages.

The paper shows that endogenous retroviruses contribute to neutrophil dysfunction and exosome-mediated pulmonary arterial hypertension.

Single-cell multi-omic profiling identifies immune dysregulation in severe COVID-19, including neutrophil hyperactivation and anti-inflammatory monocytes.