Author

A. Lawson

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 1 Plant Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:Arabidopsis· 1 Assay:cryo-EM· 1 Research Focus:drug response / drug discovery· 1 Organism:plant (other)· 1 Research Focus:protein structure prediction· 1

Frequent Co-Authors

A. Forderer· 1 shared A. Macpherson· 1 shared B. Holmes· 1 shared C. M. Deane· 1 shared D. I. Svergun· 1 shared E. Li· 1 shared E. Logemann· 1 shared J. Birtley· 1 shared

Activity by Year

2020-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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1 shared paperPlant Biology

A. Forderer

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2 papers

Recent·Most cited

A wheat resistosome defines common principles of immune receptor channels

A. Forderer, E. Li, A. Lawson, Y.-n. Deng, Y. Sun, E. Logemann, X. Zhang, J. Wen, Z. Han, J. Chang, Y.-h. Chen, P. Schulze-Lefert, J. Chai

This study reports the cryo-EM structure of the wheat CNL Sr35 resistosome and shows its structural and functional conservation with the Arabidopsis ZAR1 resistosome.

bioRxiv · Mar 23, 2022Plant Biology

The allosteric modulation of Complement C5 by knob domain peptides

A. Macpherson, M. Laabei, Z. Ahdash, M. A. Graewert, J. Birtley, S. Schulze, S. Crennell, S. Robinson, B. Holmes, V. Oleinikovas, P. H. Nilsson, J. Snowden, V. Ellis, T. E. Mollnes, C. M. Deane, , J. van den Elsen

This study shows that knob domain peptides modulate complement C5 through allosteric mechanisms, revealing new therapeutic inhibitors and introducing knob domains as low molecular weight antibody fragments.

bioRxiv · Oct 24, 2020Immunology