Author

A. Mortazavi

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2 Biochemistry· 1 Biophysics· 1 Evolutionary Biology· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 5 Approach:experimental assay· 4 Assay:bulk RNA-seq· 3 Research Focus:clustering· 3 Research Focus:cell signaling & trafficking· 2 Research Focus:cell-cell communication· 2 Research Focus:development & morphogenesis· 2 Organism:mouse· 2

Frequent Co-Authors

A. Anderson· 1 shared A. Cortez· 1 shared A. D. Briscoe· 1 shared A. Ionkina· 1 shared A. Macias-Munoz· 1 shared A. R. Najafi· 1 shared B. Sabass· 1 shared C. Feng· 1 shared

Activity by Year

2019-2024 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 4 mutual co-author links

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1 shared paperImmunology

A. Anderson

Mutual co-authors in cluster

Author profile →

6 papers

Recent·Most cited

Traction Force Microscopy with DNA FluoroCubes

A. Mortazavi, J. Jiang, P. Laric, D. Helmerich, R. Seifert, S. Gavrilovic, M. Sauer, B. Sabass

This paper introduces FluoroCubes as fiducial markers for traction force microscopy, enabling high-resolution force mapping with improved sensitivity and compatibility with TIRF microscopy.

bioRxiv · Apr 12, 2024Biophysics

Transcriptome analysis of heterogeneity in mouse model of metastatic breast cancer

A. Ionkina, G. Balderrama-Gutierrez, K. Ibanez, S. Phan, A. Cortez, A. Mortazavi, J. A. Prescher

The paper analyzes tumor heterogeneity and organ tropism in a mouse model of metastatic breast cancer using bulk and single-cell RNA-seq.

bioRxiv · May 4, 2021Cancer Biology

Multiple mechanisms of photoreceptor spectral tuning following loss of UV color vision in Heliconius butterflies

K. J. McCulloch, A. Macias-Munoz, A. Mortazavi, A. D. Briscoe

The paper examines how the loss of the UV2 photoreceptor in Heliconius butterflies has led to multiple spectral tuning mechanisms in their visual systems.

bioRxiv · Feb 23, 2021 · PreprintEvolutionary Biology

Subventricular zone/white matter microglia reconstitute the empty adult microglial niche in a dynamic wave

L. A. Hohsfield, A. R. Najafi, Y. Ghorbanian, N. Soni, J. Crapser, D. X. Figueroa Velez, S. Jiang, S. E. Royer, S. J. Kim, A. Anderson, S. P. Gandhi, A. Mortazavi, M. A. Inlay, K. N. Green

The paper depletes adult microglia using CSF1R inhibition and shows that subventricular zone/white matter myeloid cells dynamically repopulate the brain, exhibiting distinct phenotypes from endogenous microglia.

bioRxiv · Feb 17, 2021Immunology

Transcriptome-Wide Combinatorial RNA Structure Probing in Living Cells

D. Chan, C. Feng, W. England, D. Wyman, R. Flynn, X. Wang, Y. Shi, A. Mortazavi, R. Spitale

This study introduces icLASER, a method to map RNA solvent accessibility transcriptome-wide, and combines it with icSHAPE to predict RNA-protein interactions and polyadenylation sites.

bioRxiv · Mar 24, 2020 · PreprintBiochemistry

Disrupting β-catenin dependent Wnt signaling activates an invasive gene program predictive of colon cancer progression

G. T. Chen, D. F. Tifrea, R. Murad, Y. Lyou, A. Mortazavi, R. A. Edwards, M. L. Waterman

This study shows that reducing Wnt signaling in colon cancer cells increases their invasiveness and identifies gene markers predictive of poor patient outcomes.

bioRxiv · Jul 16, 2019Cancer Biology