E. Percivalle

Conversion of monoclonal IgG to dimeric and secretory IgA restores neutralizing ability and prevents infection of Omicron lineages

Engineered dimeric and secretory IgA1 neutralized Omicron variants with higher potency than parental IgG.

Tetravalent SARS-CoV-2 S1 Subunit Protein Vaccination Elicits Robust Humoral and Cellular Immune Responses in SIV-Infected Rhesus Macaque Controllers

This study evaluates a tetravalent SARS-CoV-2 S1 subunit vaccine in SIV-infected rhesus macaques, showing robust humoral and cellular immune responses, including cross-reactivity against Omicron.

SARS-CoV-2 S1 Subunit Booster Vaccination Elicits Robust Humoral Immune Responses in Aged Mice

This study shows that a S1 subunit booster vaccine enhances neutralizing antibodies and cross-reactivity against multiple SARS-CoV-2 variants in aged mice vaccinated with an adenovirus-based vaccine.

Adenovirus-Vectored SARS-CoV-2 Vaccine Expressing S1-N Fusion Protein

This paper develops a novel adenovirus-vectored SARS-CoV-2 vaccine expressing S1-N fusion protein, showing improved immunogenicity in mice against SARS-CoV-2 variants.

Immunity to SARS-CoV-2 up to 15 months after infection

This study tracks SARS-CoV-2 immunity in patients up to 15 months post-infection, showing sustained antibody and memory B/T cell responses but reduced neutralization against variants.

Bispecific antibody neutralizes circulating SARS-CoV-2 variants, prevents escape and protects mice from disease

Neutrophil extracellular traps induce the epithelial-mesenchymal transition: implications in post-COVID-19 fibrosis

This study shows that neutrophil extracellular traps (NETs) induce epithelial-mesenchymal transition (EMT) in lung cells, contributing to post-COVID-19 fibrosis.

Persistence of SARS-CoV-2 specific B- and T-cell responses in convalescent COVID-19 patients 6-8 months after the infection

This study tracks SARS-CoV-2 specific B- and T-cell responses in convalescent patients 6-8 months post-infection, finding sustained memory cell responses despite declining antibody levels.

Clinical And Analytical Performance Of An Automated Serological Test That Identifies S1/S2 Neutralizing IgG In Covid-19 Patients Semiquantitatively.

This paper evaluates an automated serological test for SARS-CoV-2 S1/S2 IgG antibodies, showing high sensitivity, specificity, and semiquantitative neutralizing capacity for clinical use.