Author

M. K. Louder

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Immunology· 5

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 5 Research Focus:host-pathogen & immune response· 4 Organism:mouse· 3 Assay:proteomics· 3 Organism:non-human primate· 2 Organism:rat· 2 Research Focus:cell type annotation· 1 Research Focus:clustering· 1

Frequent Co-Authors

J. Gorman· 3 shared K. Wiehe· 3 shared N. A. Doria-Rose· 3 shared B. C. Lin· 2 shared B. Zhang· 2 shared G.-Y. Chuang· 2 shared H. Geng· 2 shared K. O. Saunders· 2 shared

Activity by Year

2018-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 42 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

3 shared papersImmunology

J. Gorman

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Augmenting Neutralization breadth against Diverse HIV-1 by increasing the Ab-Ag interface on V2

N. Gao, Y. Gai, L. Meng, C. Wang, W. Wang, X. Li, T. Gu, M. K. Louder, N. A. Doria-Rose, K. Wiehe, A. F. Nazzari, A. S. Olia, J. Gorman, R. Rawi, W. Wu, , F. Gao

This study identifies a lineage of antibodies from infected rhesus macaques that neutralize 54% of HIV-1 strains by expanding the antibody-Env interface around the V2 loop.

bioRxiv · Aug 7, 2021 · PreprintImmunology

Rapid selection of HIV envelopes that bind to neutralizing antibody B cell lineage members with functional improbable mutations

O. Swanson, B. Rhodes, A. Wang, X. Shi-Mao, R. Parks, A. Sanzone, M. K. Louder, B. C. Lin, N. Doria-Rose, M. Bonsignori, K. O. Saunders, K. Wiehe, B. F. Haynes, M. L. Azoitei

The paper identifies a minimal set of mutations required for the function of a HIV bnAb and demonstrates in vitro selection of envelope immunogens that can bind to antibodies with these mutations.

bioRxiv · Jan 4, 2021Immunology

Recapitulation of HIV-1 Env-Antibody Coevolution in Macaques Leading to Neutralization Breadth

R. S. Roark, H. Li, W. B. Williams, H. Chug, R. D. Mason, J. Gorman, S. Wang, F.-H. Lee, J. Rando, M. Bonsignori, K.-K. Hwang, K. O. Saunders, K. Wiehe, M. A. Moody, P. T. Hraber, , C. A Schramm

Virus-antibody coevolution in rhesus macaques recapitulates developmental features of human antibodies.

bioRxiv · Aug 5, 2020Immunology

SARS-CoV-2 mRNA Vaccine Development Enabled by Prototype Pathogen Preparedness

K. S. Corbett, D. Edwards, S. R. Leist, O. M. Abiona, S. Boyoglu-Barnum, R. A. Gillespie, S. Himansu, A. Schafer, C. T. Ziwawo, A. T. DiPiazza, K. H. Dinnon, S. M. Elbashir, C. A. Shaw, A. Woods, E. J. Fritch, , Wang

This paper describes the development of an mRNA vaccine (mRNA-1273) against SARS-CoV-2, showing it induces neutralizing antibodies and CD8 T cell responses and protects mice from infection.

bioRxiv · Jun 11, 2020Immunology

Epitope-based vaccine design yields fusion peptide-directed antibodies that neutralize diverse strains of HIV-1

K. Xu, P. Acharya, R. Kong, C. Cheng, G.-Y. Chuang, K. Liu, M. K. Louder, S. O Dell, R. Rawi, M. Sastry, C.-H. Shen, B. Zhang, T. Zhou, M. Asokan, R. T. Bailer, , McDermott

This study shows that targeting the HIV-1 fusion peptide with specific immunogens induces cross-clade neutralizing antibodies in animals.

bioRxiv · Apr 23, 2018Immunology