Author

A. Schmid

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 7 Biochemistry· 1 Biophysics· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 7 Research Focus:cell type annotation· 4 Organism:multiple species· 3 Research Focus:chromatin & epigenetic regulation· 2 Research Focus:differential expression· 2 Assay:DNA methylation· 2 Research Focus:host-pathogen & immune response· 2 Organism:human· 2

Frequent Co-Authors

A. Bisson· 2 shared C. L. Darnell· 2 shared E. C. Garner· 2 shared J. Zheng· 2 shared K.-P. Hopfner· 2 shared P. Korber· 2 shared A. Dodge· 1 shared A. Lammers· 1 shared

Activity by Year

2020-2024 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 12 mutual co-author links

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2 shared papersMicrobiology

A. Bisson

Mutual co-authors in cluster

Author profile →

9 papers

Recent·Most cited

Released Bacterial ATP Shapes Local and Systemic Inflammation during Abdominal Sepsis

D. Spari, A. Schmid, D. Sanchez-Taltavull, S. Murugan, K. Keller, N. Ennaciri, L. Salm, D. Stroka, G. Beldi

This study investigates how bacteria release ATP during sepsis and shows that bacterial ATP suppresses local immune responses and exacerbates systemic inflammation through outer membrane vesicles.

bioRxiv · Mar 7, 2024Microbiology

Halofilins as Emerging Bactofilin Families of Archaeal Cell Shape Plasticity Orchestrators

Z. Curtis, P. Escudeiro, J. L. Mallon, O. Leland, T. Rados, A. Dodge, K. Andre, J. Kwak, K. Yun, B. Isaac, M. Martinez Pastor, A. Schmid, M. Pohlschroder, V. Alva, A. Bisson

This study identifies and characterizes two new families of archaeal bactofilins, HalA and HalB, showing their roles in shaping cell morphology and curvature in Haloferax volcanii.

bioRxiv · Jan 22, 2024Microbiology

Contemporary HIV-1 consensus Env with redesigned hypervariable loops promote antibody binding

H. Bai, E. Lewitus, Y. Li, V. Dussupt, B. Slike, L. Mendez-Rivera, A. Schmid, L. Wieczorek, V. Polonis, S. J. Krebs, J. A. Ake, S. Vasan, M. G. Joyce, S. Townsley, M. Rolland

The paper redesigns hypervariable loops in HIV-1 Env consensus sequences to enhance antibody binding and improve vaccine antigen design.

bioRxiv · Nov 19, 2023 · PreprintMicrobiology

A conserved transcription factor controls gluconeogenesis via distinct targets in hypersaline-adapted archaea with diverse metabolic capabilities

R. K. Hackley, A. Vreudenhil, C. L. Darnell, A. Schmid

The paper investigates the role of TrmB in regulating gluconeogenesis in two Haloarchaea with different metabolic capabilities, finding divergent regulatory mechanisms.

bioRxiv · Aug 19, 2023Microbiology

Salactin, a dynamically unstable actin homolog in Haloarchaea

J. Zheng, A. Lammers, J. Mallon, T. Litschel, E. Moody, D. A. R. Diaz, A. Schmid, T. A. Williams, A. Bisson, E. C. Garner

This study identifies and characterizes Salactin, an actin homolog in Haloarchaea, showing it forms dynamically unstable filaments and is involved in chromosomal segregation under low-ploidy conditions.

bioRxiv · Mar 9, 2023Microbiology

TrmB family transcription factor as a thiol-based regulator of oxidative stress response

P. Mondragon, S. Hwang, L. Kasirajan, R. Oyetoro, A. Nasthas, E. Winters, R. L. Couto-Rodriguez, A. Schmid, J. A. Maupin-Furlow

This paper identifies TrmB-like proteins as thiol-based regulators of oxidative stress response in archaea, showing OxsR functions as both activator and repressor during hypochlorite stress.

bioRxiv · Mar 5, 2022Microbiology

Sequence- and chemical specificity define the functional landscape of intrinsically disordered regions

I. Langstein-Skora, A. Schmid, F. Huth, D. Shabani, L. Spechtenhauser, M. Likhodeeva, F. Kunert, F. J. Metzner, R. J. Emenecker, M. O. G. Richardson, W. Aftab, M. J. Goetz, S. K. Payer, N. Pietrantoni, V. Sjenicic, , A. S. Holehouse

The paper investigates how sequence- and chemical specificity enable functional IDR diversity despite poor sequence conservation.

bioRxiv · Feb 10, 2022Biophysics

The ribbon-helix-helix domain proteins CdrS and CdrL regulate cell division in archaea

C. L. Darnell, J. Zheng, S. Wilson, R. M. Bertoli, A. W. Bisson-Filho, E. C. Garner, A. Schmid

This study identifies and characterizes the CdrSL gene regulatory network in archaea, showing its role in regulating cell division through transcriptional control of FtsZ2.

bioRxiv · Jun 16, 2020 · PreprintMicrobiology

Ruler elements in chromatin remodelers set nucleosome array spacing and phasing

E. Oberbeckmann, V. Niebauer, S. Watanabe, L. Farnung, M. Moldt, A. Schmid, P. Cramer, C. L. Peterson, S. Eustermann, K.-P. Hopfner, P. Korber

The paper identifies a ruler element in chromatin remodelers that determines nucleosome spacing and phasing in Saccharomyces cerevisiae.

bioRxiv · Feb 28, 2020Biochemistry