ImmunologybioRxivPreprint
A Germinal Center Checkpoint of AIRE in B Cells Limits Antibody Diversification
J. Z. Zhou, B. Pei, G. Sun…·K. Chen
This study identifies AIRE as a checkpoint in germinal center B cells that limits antibody diversification by inhibiting AID function, leading to autoimmunity and impaired immune responses.
DOI 10.1101/2024.01.10.574926