Author

B. W. Loo

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 3

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:mouse· 3 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Research Focus:development & morphogenesis· 1 Assay:electrophysiology· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

A. C. Koong· 2 shared L. Skinner· 2 shared R. Manjappa· 2 shared A. Delahoussaye· 1 shared A. Kim· 1 shared A. S. Yu· 1 shared A. Yu· 1 shared B. C. Lau· 1 shared

Activity by Year

2019-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersCancer Biology

A. C. Koong

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3 papers

Recent·Most cited

Redefining FLASH RT: the impact of mean dose rate and dose per pulse in the gastrointestinal tract

K. Liu, T. Waldrop, E. Aguilar, N. Mims, D. Neill, A. Delahoussaye, Z. Li, D. Swanson, S. H. Lin, A. C. Koong, C. M. Taniguchi, B. W. Loo, D. Mitra, E. Schueler

This study evaluates how varying radiation beam parameters affect gastrointestinal toxicity and tumor response in mice, finding that high dose per pulse and ultra-high dose rate independently reduce toxicity while maintaining tumor control.

bioRxiv · Apr 19, 2024Cancer Biology

A multi-institutional study to investigate the sparing effect after whole brain electron FLASH in mice: Reproducibility and temporal evolution of functional, electrophysiological, and neurogenic endpoints

O. G. G. Drayson, S. Melemenidis, N. Katila, V. Viswanathan, E. Kramar, R. Zhang, R. Kim, N. Ru, B. Petit, S. Dutt, R. Manjappa, R. Ashraf, B. C. Lau, L. Soto, L. Skinner, , C. Limoli

This study evaluates the reproducibility and temporal evolution of FLASH and CONV irradiation effects on mice, showing FLASH sparing at late but not early time points.

bioRxiv · Jan 25, 2024Cancer Biology

FLASH irradiation enhances the therapeutic index of abdominal radiotherapy for the treatment of ovarian cancer

K. Levy, S. Natarajan, J. Wang, S. Chow, J. T. Eggold, P. Loo, R. Manjappa, F. M. Lartey, E. Schüler, L. Skinner, M. Rafat, R. Ko, A. Kim, D. Al Rawi, R. von Eyben, , E. B. Rankin

This study shows FLASH irradiation reduces intestinal injury while maintaining ovarian cancer treatment efficacy in preclinical models.

bioRxiv · Dec 12, 2019 · PreprintCancer Biology