Author

C. Au

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 3

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:mouse· 3 Assay:bulk RNA-seq· 2 Research Focus:cell signaling & trafficking· 2 Research Focus:host-pathogen & immune response· 2 Approach:statistical model· 2 Research Focus:cell type annotation· 1 Assay:ChIP-seq· 1

Frequent Co-Authors

D. R. Littman· 3 shared R. Yi· 2 shared A. C. Kimmelman· 1 shared A. Teghanemt· 1 shared C. Galan· 1 shared C. Ng· 1 shared D. Li· 1 shared H. L. Keen· 1 shared

Activity by Year

2017-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 23 mutual co-author links

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3 shared papersImmunology

D. R. Littman

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Author profile →

3 papers

Recent·Most cited

Epigenetic Programming during thymic development sets the stage for optimal function in effector T cells via DNA demethylation

A. Teghanemt, P. Pulipati, K. Day, M. S. Yorek, R. Yi, K. M. Misel, H. L. Keen, C. Au, T. Maretzky, P. Gurung, D. R. Littman, P. D. Issuree

The paper shows DNA demethylation during thymic development is essential for proper function of stimulus-responsive elements in effector T cells, impacting gene expression and immune response.

bioRxiv · May 3, 2021 · PreprintImmunology

Niche-selective inhibition of pathogenic Th17 cells by targeting metabolic redundancy

L. Wu, K. E. R. Hollinshead, Y. Hao, C. Au, L. Kroehling, C. Ng, W.-y. Lin, D. Li, H. M. Silva, J. Shin, J. J. Lafaille, R. Possemato, M. E. Pacold, T. Y. Papagiannakopoulos, A. C. Kimmelman, , D. R. Littman

This study shows that targeting Gpi1 selectively inhibits pathogenic Th17 cells in autoimmune diseases while sparing homeostatic Th17 cells.

bioRxiv · Jun 10, 2020Immunology

c-Maf-dependent regulatory T cells mediate immunological tolerance to intestinal microbiota

M. Xu, M. Pokrovskii, Y. Ding, R. Yi, C. Au, C. Galan, R. Bonneau, D. R. Littman

This study identifies c-Maf-dependent regulatory T cells that suppress inflammation caused by the pathobiont Helicobacter hepaticus, preventing colitis in mice.

bioRxiv · Apr 22, 2017Immunology