In vitro efficacy and in vivo toxicity and retention of targeted nanoformulated carboplatin in a sustained release carrier for treatment of osteosarcoma
K. Day, M. Risselada, M. Sokolsky
bioRxiv · May 2, 2024 · PreprintCancer Biology
Author
K. Day
Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.
Biology Disciplines
Click to filter author papersSignature Assays, Organisms & Methods
Click to filter · or open tagActivity by Year
2018-2024 · peak 2/yrCo-Author Collaboration Network
10 top collaborators · 12 mutual co-author linksFocal author (center)Selected co-authorORCID co-authorUnlinked name
Curved chords = mutual co-authorship9 papers
Recent·Most cited
Programming Probiotics: Diet-responsive gene expression and colonization control in engineered S. boulardii
D. Durmusoglu, D. J. Haller, I. S. Al'Abri, K. Day, C. Sands, A. S. Clark, A. San Miguel, R. Vazquez-Uribe, M. O. Sommer, N. C. Crook
This study engineers S. boulardii to control gene expression and gut residence time via diet-responsive systems, enabling precise therapeutic delivery in the mouse gut.
bioRxiv · Nov 17, 2023Bioengineering
Ubiquitin-driven protein condensation initiates clathrin-mediated endocytosis
F. Yuan, S. Gollapudi, K. Day, G. Ashby, A. Sangani, B. Malady, L. Wang, E. M. Lafer, J. Huibregtse, J. Stachowiak
This paper shows that ubiquitin stabilizes Eps15 condensates, which are essential for clathrin-mediated endocytosis, and that ubiquitylation regulates the dynamics of endocytic assemblies.
bioRxiv · Aug 21, 2023 · PreprintCell Biology
Mesenchymal Progenitors set the homeostatic inflammatory milieu via the TAK1-NFkB axis.
M. Theret, M. Messing, Z. White, L. W. Henry, L. Rempel, M. Hamer, J. Hashimoto, F. F. Li, J. Brassard, Y. Li, E. Sauge, S. Shin, K. Day, M. Uppal, M. Low, , F. M. V. Rossi
This study shows mesenchymal progenitors regulate the balance between type 1 and type 2 inflammation via the TAK1-NFkB pathway, with implications for inflammatory diseases.
bioRxiv · Dec 11, 2022 · PreprintCell Biology
Epigenetic Programming during thymic development sets the stage for optimal function in effector T cells via DNA demethylation
A. Teghanemt, P. Pulipati, K. Day, M. S. Yorek, R. Yi, K. M. Misel, H. L. Keen, C. Au, T. Maretzky, P. Gurung, D. R. Littman, P. D. Issuree
The paper shows DNA demethylation during thymic development is essential for proper function of stimulus-responsive elements in effector T cells, impacting gene expression and immune response.
bioRxiv · May 3, 2021 · PreprintImmunology
Frequency-dependent competition between strains imparts resilience to perturbations in a model of Plasmodium falciparum malaria transmission.
Q. He, S. Pilosof, K. E. Tiedje, K. Day, M. Pascual
This paper shows that frequency-dependent selection increases resilience of malaria transmission systems to intervention compared to neutral processes.
bioRxiv · Dec 22, 2020Ecology
A scalable method for identifying recombinants from unaligned sequences
Q. Feng, K. Tiedje, S. Ruybal-Pesantez, G. Tonkin-Hill, M. Duffy, K. Day, H. Shim, Y.-b. Chan
This paper introduces a scalable method to identify recombinant sequences from unaligned data, demonstrating its effectiveness on malaria parasite var genes.
bioRxiv · Nov 18, 2020Evolutionary Biology
Competition for hosts modulates vast antigenic diversity to generate persistent strain structure in Plasmodium falciparum
S. Pilosof, Q. He, K. E. Tiedje, S. Ruybal-Pesantez, K. Day, M. Pascual
The paper shows immune selection generates persistent genetic modules in Plasmodium falciparum, which function as dynamic strains in host immune space.
bioRxiv · Sep 18, 2018Ecology
Networks of genetic similarity reveal non-neutral processes shape strain structure in Plasmodium falciparum
Q. He, S. Pilosof, K. E. Tiedje, S. Ruybal-Pesantez, Y. Artzy-Randrup, E. B. Baskerville, K. Day, M. Pascual
The paper develops neutral models to analyze genetic structure in Plasmodium falciparum and finds non-neutral strain organization in a Ghanaian population.
bioRxiv · Apr 10, 2018Ecology