Author

C. Burns

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 3 Immunology· 2

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 5 Approach:experimental assay· 4 Research Focus:differential expression· 3 Organism:mouse· 3 Research Focus:cell signaling & trafficking· 2 Research Focus:development & morphogenesis· 2 Assay:flow cytometry· 2 Organism:human· 2

Frequent Co-Authors

J. A. Spencer· 3 shared A. Fasano· 1 shared A. Kumanogoh· 1 shared A. M. Lozano· 1 shared A. Pradeep· 1 shared A. Scialdone· 1 shared B. Chicana· 1 shared B. Gottgens· 1 shared

Activity by Year

2019-2022 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 23 mutual co-author links

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3 shared papersImmunology

J. A. Spencer

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Thymic mesenchymal niche cells drive T cell immune regeneration

K. Gustafsson, S. Isaev, K. A. Kooshesh, N. Baryawno, K. D. Kokkaliaris, N. Severe, T. Zhao, E. W. Scadden, J. A. Spencer, C. Burns, K. Akilan, N. Barkas, H. Gessessew, C. P. Lin, P. V. Kharchenko, D. Scadden

This study identifies a thymic mesenchymal niche cell subset that supports T cell regeneration and shows its therapeutic potential in reversing thymic atrophy.

bioRxiv · Oct 12, 2022Immunology

Towards optimised extracellular vesicle proteomics from cerebrospinal fluid

P. Kangas, T. A. Nyman, L. Metsähonkala, C. Burns, R. Tempest, T. Williams, J. Karttunen, T. S. Jokinen

This study validates an UF-SEC method for isolating EVs from canine CSF and shows that proteomic analysis can be performed from as little as 0.5ml of CSF.

bioRxiv · Sep 27, 2022Cell Biology

Myeloid-biased HSC require Semaphorin 4A from the bone marrow niche for self-renewal under stress and life-long persistence

D. Toghani, S. Zeng, E. Mahammadov, E. I. Crosse, N. Seyedhassantehrani, C. Burns, D. Gravano, S. Radtke, H.-P. Kiem, S. Rodriguez, N. Carlesso, A. Pradeep, N. K. Wilson, S. J. Kinston, B. Gottgens, , L. Silberstein

This study identifies Sema4A as a critical niche factor required for myeloid-biased HSC self-renewal and long-term persistence under stress.

bioRxiv · Jan 12, 2022 · PreprintCell Biology

Deletion of Vhl in Dmp1-expressing cells causes microenvironmental impairment of B cell lymphopoiesis

B. Chicana, N. Abbasizadeh, C. Burns, H. Taglinao, J. A. Spencer, J. O. Manilay

This study shows that deleting Vhl in Dmp1-expressing cells impairs the B cell microenvironment in bone marrow, leading to B cell developmental defects.

bioRxiv · Sep 10, 2021Immunology

VPS41 recessive mutation causes ataxia and dystonia with retinal dystrophy and mental retardation by inhibiting HOPS function and mTORC1 signaling

R. E. N. van der Welle, R. Jobling, C. Burns, P. Sanza, C. ten Brink, A. Fasano, L. Chen, F. J. Zwartkruis, S. Zwakenberg, E. F. Griffin, J. van der Beek, T. Veenendaal, N. Liv, S. Blaser, C. Sepulveda, , J. Klumperman

This paper identifies VPS41 mutations causing neurodegenerative disease by disrupting HOPS function and mTORC1 signaling, leading to lysosomal dysfunction and impaired autophagy.

bioRxiv · Dec 18, 2019 · PreprintCell Biology