S. Zeng

Diversified global vegetable oil production can mitigate climate change and achieve socio-environmental co-benefits

This paper assesses the environmental and economic impacts of global vegetable oil production and shows that diversification can reduce emissions and increase farmer income.

Elucidating the kinetic and thermodynamic insight into regulation of glycolysis by lactate dehydrogenase and its impact on tricarboxylic acid cycle and oxidative phosphorylation in cancer cells

This study investigates how lactate dehydrogenase (LDH) regulates glycolysis, TCA cycle, and oxidative phosphorylation in cancer cells through kinetic and thermodynamic mechanisms, showing that LDH inhibition disrupts metabolic pathways and induces cell death under hypoxia.

Comparison of therapeutic effects between pulsed field ablation and cryoballoon ablation in the treatment of atrial fibrillation: a systematic review and me-ta-analysis

This study compares pulsed field ablation (PFA) and cryoballoon ablation (CBA) for atrial fibrillation treatment, finding PFA reduces surgical time and complications but not arrhythmia recurrence.

Heterogeneous hybrid immunity against Omicron variant JN.1 at 11 months following breakthrough infection

This study evaluates hybrid immunity against the Omicron variant JN.1 11 months after breakthrough infection, showing heterogeneous responses and increased neutralization following reinfection.

Establishment of an Inhalation Administration Noninvasive Murine Model for Rapidly Testing Drug Activity against Mycobacterium tuberculosis

This paper develops a non-invasive murine inhalation model using autoluminescent M. tuberculosis to rapidly assess drug efficacy against tuberculosis.

A CRISPR-Nonhomologous End-Joining-based strategy for rapid and efficient gene disruption in Mycobacterium abscessus

This paper introduces a CRISPR-NHEJ strategy for efficient gene disruption in Mycobacterium abscessus and shows that homologous recombination and single-strand annealing components are required for NHEJ repair.

Phosphorylation and O-GlcNAcylation at the same alpha-synuclein site generate distinct fibril structures

This study shows that phosphorylation and O-GlcNAcylation at the same alpha-synuclein site generate distinct fibril structures with different neurotoxicity and propagation properties.

ABI5-FLZ13 Module Transcriptionally Represses Growth-related Genes to Delay Seed Germination in Response to ABA

This study identifies FLZ13 as an ABI5-interacting protein that co-represses growth-related genes to delay seed germination in response to ABA.

GLKs directly regulate carotenoid biosynthesis via interacting with GBFs in nuclear condensates in plants

This study identifies GLKs as regulators of carotenoid biosynthesis through GBF-dependent transcriptional activation and phase separation-mediated nuclear condensates.

Early life adversity and adult social relationships have independent effects on survival in a wild animal model of aging

The paper shows early life adversity and adult social isolation independently reduce survival in wild baboons, supporting both health selection and social causation hypotheses.

The thermodynamic state of aerobic glycolytic flux plays a critical role in stabilizing aerobic glycolytic flux of cancer cells

This study identifies the thermodynamic state of aerobic glycolysis (TSAG) as a system property that stabilizes glycolytic flux in cancer cells, showing it resists perturbations and requires both enzyme inhibition and TSAG disruption for effective AG inhibition.

Myeloid-biased HSC require Semaphorin 4A from the bone marrow niche for self-renewal under stress and life-long persistence

This study identifies Sema4A as a critical niche factor required for myeloid-biased HSC self-renewal and long-term persistence under stress.

Direct regulation of cell cycle regulatory gene expression by NtrX to promote Sinorhizobium meliloti cell division

This study shows NtrX regulates CtrA signaling network genes in S. meliloti, affecting cell division and linking nitrogen metabolism to cell cycle control.

Polypeptides IGF-1C and P24 synergistically promote osteogenic differentiation of bone marrow mesenchymal stem cells in vitro through the p38 and JNK signaling pathways

This study shows that IGF-1C and P24 together enhance osteogenic differentiation of BMSCs by activating p38 and JNK pathways.

MAPK Pathway Inhibition as A Rational Therapeutic Strategy for MiR-138-5p/PAQR3 Dysregulation-mediated Epirubicin Resistance in Triple-negative Breast Cancer

This study identifies PAQR3 as a predictor of epirubicin response in TNBC and shows that MAPK inhibition can reverse resistance caused by miR-138-5p-mediated PAQR3 downregulation.

Integrative proteomic and phosphoproteomic analysis of granulosa cells during follicular atresia in porcine

This study identifies differentially expressed proteins and phosphosites in porcine granulosa cells during follicular atresia, revealing potential biomarkers and pathways involved in the process.

Nature and effective range of non-cell autonomous activator and inhibitor peptides specifying plant stomatal patterning

The paper quantitatively characterizes the non-cell autonomous effects of EPF1 and Stomagen on 2-D stomatal patterning using mosaic sectors and a computational pipeline.

Blocking antibodies against SARS-CoV-2 RBD isolated from a phage display antibody library using a competitive biopanning strategy

This paper isolates blocking antibodies against SARS-CoV-2 RBD using a competitive biopanning strategy, identifying a high-affinity antibody with potent neutralizing activity.

The Manifold Actions of Signaling Peptides on Subcellular Dynamics of a Receptor Specify Stomatal Cell Fate

The paper shows how different signaling peptides alter the subcellular dynamics of a receptor to determine stomatal cell fate in plants.

Fast, 3D isotropic imaging of whole mouse brain using multi-1 angle-resolved subvoxel SPIM

The paper was withdrawn due to inaccurate descriptions of other techniques in the manuscript.