Author

C. Cicala

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 4 Microbiology· 1

Signature Assays, Organisms & Methods

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Research Focus:host-pathogen & immune response· 5 Approach:experimental assay· 4 Assay:bulk RNA-seq· 2 Organism:human· 2 Organism:non-human primate· 2 Assay:flow cytometry· 1 Organism:mouse· 1 Assay:proteomics· 1

Frequent Co-Authors

J. Arthos· 5 shared D. Bose· 2 shared E. Marinelli· 2 shared F. J. Villinger· 2 shared I. Frank· 2 shared M. Arainga· 2 shared R. Lorenzo-Redondo· 2 shared T. J. Hope· 2 shared

Activity by Year

2018-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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5 shared papersImmunology

J. Arthos

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

TGF-β blockade drives a transitional effector phenotype in T cells reversing SIV latency and decreasing SIV reservoirs in vivo

J. Kime, D. Bose, M. Arainga, M. R. Haque, C. M. Fennessey, R. A. Caddell, Y. Thomas, D. E. Ferrell, S. Ali, E. Grody, Y. Goyal, C. Cicala, J. Arthos, B. F. Keele, M. Vaccari, , E. Marinelli

TGF-β blockade with galunisertib reverses SIV latency, reduces viral reservoirs, and enhances immune responses in ART-treated macaques without systemic inflammation.

bioRxiv · Sep 5, 2023Immunology

Murine Alveolar Macrophages Rapidly Accumulate Intranasally Administered SARS-CoV-2 Spike Protein leading to Neutrophil Recruitment and Damage

C. Park, I.-Y. Hwang, S. L.-S. Yan, S. Vimonpatranon, D. Wei, D. Van Ryk, A. Girard, C. Cicala, J. Arthos, J. H. Kehrl

This study shows that intranasal SARS-CoV-2 Spike protein is rapidly taken up by murine alveolar macrophages, leading to neutrophil recruitment and tissue damage.

bioRxiv · Mar 13, 2023Immunology

Blockade of TGF-β signaling reactivates HIV-1/SIV reservoirs and immune responses in vivo

S. Samer, Y. Thomas, M. Arainga, C. Carter, L. M. Shirreff, M. S. Arif, J. M. Avitia, I. Frank, M. D. McRaven, C. T. Thuruthiyil, V. B. Heybeli, M. R. Anderson, B. Owen, A. Gaisin, D. Bose, , E. Marinelli

This study shows that blocking TGF-β signaling increases HIV-1 and SIV reactivation and boosts immune responses in infected individuals on ART.

bioRxiv · May 13, 2022Immunology

SARS-CoV-2 genomic and quasispecies analyses in cancer patients reveal relaxed intrahost virus evolution

J. Siqueira, L. R. Goes, B. M. Alves, P. S. de Carvalho, C. Cicala, J. Arthos, J. P. B. Viola, A. C. de Melo, M. A. Soares, INCA COVID-19 Task Force (names of participants listed in the acknowledgements section number of cha

This study compares intrahost SARS-CoV-2 genetic diversity between cancer patients and healthcare workers, finding higher diversity in cancer patients which may contribute to more severe COVID-19 outcomes.

bioRxiv · Aug 26, 2020 · PreprintMicrobiology

Protection of rhesus macaques against vaginal SHIV challenges by VRC01 and an anti-α4β7 antibody

G. Calenda, I. Frank, G. Arrode-Bruses, A. Pegu, K. Wang, J. Arthos, C. Cicala, B. Grasperge, J. L. Blanchard, S. Maldonado, K. Roberts, A. Gettie, A. S. Fauci, J. R. Mascola, E. Martinelli

This study shows that combining VRC01 and Rh-4β7 antibodies delays SHIV infection, preserves CD4+ T cells, and alters immune responses in macaques.

bioRxiv · Dec 11, 2018 · PreprintImmunology