Author

C. Clausen

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 2

Signature Assays, Organisms & Methods

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Approach:deep learning· 2 Research Focus:drug response / drug discovery· 2 Organism:human· 2 Assay:electrophysiology· 1 Approach:statistical model· 1 Assay:structural biology· 1

Frequent Co-Authors

A. A. Thomas· 1 shared A. Schlessinger· 1 shared D. B. Silva· 1 shared G. Zhang· 1 shared H. Liang· 1 shared H. Z. Wang· 1 shared I. S. Cohen· 1 shared J. Bohlke· 1 shared

Activity by Year

2021-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperBiophysics

A. A. Thomas

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2 papers

Recent·Most cited

Describing Inhibitor Specificity for the Amino Acid Transporter LAT1 from Metainference Simulations

K. Hutchinson, D. B. Silva, J. Bohlke, C. Clausen, A. A. Thomas, M. Bonomi, A. Schlessinger

This study uses metainference MD simulations, molecular docking, and experiments to identify critical residues and druggable pockets in LAT1, leading to the discovery of new inhibitors.

bioRxiv · May 3, 2022Biophysics

Modulating the voltage sensor of a cardiac potassium channel shows antiarrhythmic effects

Y. Lin, S. Z. Grinter, Z. Lu, X. Xu, H. Z. Wang, H. Liang, P. Hou, J. Gao, C. Clausen, J. Shi, W. Zhao, Z. Ma, Y. Liu, K. M. White, L. Zhao, , J. Cui

This study identifies C28 as a compound that modulates IKs channel voltage sensor activation, reversing drug-induced APD prolongation without affecting normal APD.

bioRxiv · Feb 25, 2021Biophysics