Author

C. E. B. Ong

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Immunology· 3

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 3 Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 2 Research Focus:host-pathogen & immune response· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:differential expression· 1 Organism:Drosophila· 1

Frequent Co-Authors

A. B. Lyons· 3 shared A. S. Flies· 3 shared G. M. Woods· 3 shared A. L. Patchett· 2 shared J. M. Darby· 2 shared G.-S. Liu· 1 shared H. Siddle· 1 shared J. Chen· 1 shared

Activity by Year

2020-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 35 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

3 shared papersImmunology

A. B. Lyons

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

ImmunologybioRxivPreprintJul 14, 2021

CIITA induces expression of MHC-I and MHC-II in transmissible cancers

C. E. B. Ong, Y. Cheng, H. Siddle…·A. S. Flies

This paper shows that CIITA upregulates MHC-I and MHC-II in transmissible cancers, with differential protein expression and functional implications for immune evasion.

DOI 10.1101/2021.07.14.452299

bulk RNA-seqexperimental assay

𝕏 PostBluesky

ImmunologybioRxivSep 6, 2020

NLRC5 regulates expression of MHC-I and provides a target for anti-tumor immunity in transmissible cancers

C. E. B. Ong, A. L. Patchett, J. M. Darby…·A. S. Flies

This study shows NLRC5 upregulates MHC-I in transmissible cancers, making MHC-I a target for anti-tumor immunity and informing immunotherapy strategies.

DOI 10.1007/s00432-021-03601-x

Drosophilabulk RNA-seq

𝕏 PostBluesky

ImmunologybioRxivJan 3, 2020

A novel system to map protein interactions reveals evolutionarily conserved immune evasion pathways on transmissible cancers

A. S. Flies, J. M. Darby, P. R. Lennard…·A. L. Patchett

The paper develops a reagent method to study immune checkpoints in non-model species and identifies conserved immune evasion pathways in transmissible cancers.

DOI 10.1126/sciadv.aba5031

mousehuman

𝕏 PostBluesky