Author
Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.
6 papers
Recent·Most cited
C. Espejo, R. Wilson, R. J. Pye…·A. B. Lyons
The paper identifies cathelicidin-3 in serum extracellular vesicles as a biomarker for early diagnosis of DFTD in Tasmanian devils with high sensitivity and specificity.
C. E. B. Ong, Y. Cheng, H. Siddle…·A. S. Flies
This paper shows that CIITA upregulates MHC-I and MHC-II in transmissible cancers, with differential protein expression and functional implications for immune evasion.
C. Espejo, R. Wilson, G. M. Woods…·A. B. Lyons
This study analyzes extracellular vesicles from Tasmanian devil cancers to identify markers of metastasis and differential aggressiveness between two cancer types.
C. E. B. Ong, A. L. Patchett, J. M. Darby…·A. S. Flies
This study shows NLRC5 upregulates MHC-I in transmissible cancers, making MHC-I a target for anti-tumor immunity and informing immunotherapy strategies.
C. Wong, J. M. Darby, P. R. Murphy…·A. S. Flies
This study shows Tasmanian devil CTLA4 and CD28 can capture CD80 and CD86 from adjacent cells, similar to other species, suggesting potential for checkpoint immunotherapy in divergent species.
A. S. Flies, J. M. Darby, P. R. Lennard…·A. L. Patchett
The paper develops a reagent method to study immune checkpoints in non-model species and identifies conserved immune evasion pathways in transmissible cancers.