Author

C. Garcia-Cabau

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 2 Cell Biology· 2 Biochemistry· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 5 Organism:human· 3 Organism:C. elegans· 2 Research Focus:cell signaling & trafficking· 2 Research Focus:cell type annotation· 2 Research Focus:development & morphogenesis· 2 Assay:proteomics· 2 Research Focus:cancer & tumor microenvironment· 1

Frequent Co-Authors

X. Salvatella· 5 shared B. Mateos· 2 shared F. Catala-Castro· 2 shared J. Garcia· 2 shared M. Krieg· 2 shared N. Sanfeliu-Cerdan· 2 shared A. Balaceanu· 1 shared A. Banuelos· 1 shared

Activity by Year

2022-2023 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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5 shared papersBiophysics

X. Salvatella

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Measuring age-dependent viscoelastic properties of organelles, cells and organisms via Time-Shared Optical TweezerMicrorheology

F. Catala-Castro, S. Ortiz-Vasquez, C. Martinez-Fernandez, F. Pezzano, C. Garcia-Cabau, M. Fernandez-Campo, N. Sanfeliu-Cerdan, S. Jimenez-Delgado, X. Salvatella, V. Ruprecht, P. A. Frigeri, M. Krieg

This paper introduces a time-shared optical tweezer microrheology method to measure age-dependent viscoelastic properties of biological materials, demonstrating its application in biomolecular condensates, zebrafish cells, and C. elegans.

bioRxiv · Oct 17, 2023 · PreprintBiophysics

Kinetic stabilization of translation-repression condensates by a neuron-specific microexon

C. Garcia-Cabau, A. Bartomeu, G. Tesei, K. C. Cheung, J. Pose-Utrilla, S. Pico, A. Balaceanu, B. Duran-Arque, M. Fernandez-Alfara, J. Martin, C. De Pace, L. Ruiz-Perez, J. Garcia, G. Battaglia, J. J. Lucas, , X. Salvatella

The paper shows that a neuron-specific microexon in CPEB4 stabilizes translation-repression condensates by competing with aggregation, enabling reversible regulation of gene expression in neurons.

bioRxiv · Mar 19, 2023Biophysics

Rational optimization of a transcription factor activation domain inhibitor

S. Basu, P. Martinez-Cristobal, M. Pesarrodona, M. Frigole-Vivas, E. Szulc, M. Lewis, A. Banuelos, C. Sanchez-Zarzalejo, S. Bielskute, J. Zhu, K. Pombo-Garcia, C. Garcia-Cabau, C. Batlle, B. Mateos, M. Biesaga, , X. Salvatella

This study optimizes a small molecule inhibitor targeting the aromatic-rich activation domain of the androgen receptor, showing improved affinity and antitumorigenic effects in prostate cancer models.

bioRxiv · Aug 18, 2022Biochemistry

A rigidity phase transition of Stomatin condensates governs a switch from transport to mechanotransduction

N. Sanfeliu-Cerdan, B. Mateos, C. Garcia-Cabau, F. Catala-Castro, M. Ribera, I. Ruider, M. Porta-de-la-Riva, S. Wieser, X. Salvatella, M. Krieg

The paper shows that MEC-2 Stomatin undergoes a rigidity phase transition in C. elegans, switching between transport and mechanotransduction functions.

bioRxiv · Jul 8, 2022 · PreprintCell Biology

Sorting of secretory proteins at the trans-Golgi network by human TGN46

P. Lujan, C. Garcia-Cabau, Y. Wakana, J. Vera Lillo, C. Rodilla-Ramirez, H. Sugiura, V. Malhotra, X. Salvatella, M. F. Garcia-Parajo, F. Campelo

This study identifies TGN46 as a receptor for sorting secretory cargo protein PAUF into TGN-to-plasma membrane carriers, showing its lumenal domain is essential for cargo sorting.

bioRxiv · Apr 20, 2022 · PreprintCell Biology